CAS 5908-99-6|Atropine sulfate monohydrate
| Common Name | Atropine sulfate monohydrate | ||
|---|---|---|---|
| CAS Number | 5908-99-6 | Molecular Weight | 387.45 |
| Density | / | Boiling Point | 429.8ºC at 760mmHg |
| Molecular Formula | C17H25NO7S | Melting Point | 189-192 °C (A)(lit.) |
| MSDS | ChineseUSA | Flash Point | 213.7ºC |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | Atropine sulfate monohydrate |
|---|---|
| Synonym | More Synonyms |
Atropine sulfate monohydrate BiologicalActivity
| Description | Atropine sulfate monohydrate is a competitive muscarinic acetylcholine receptor antagonist.Target: mAChRAtropine is a naturally occurring tropane alkaloid extracted from deadly nightshade (Atropa belladonna), Jimson weed (Datura stramonium), mandrake (Mandragora officinarum) and other plants of the family Solanaceae. Atropine is a competitive antagonist of the muscarinic acetylcholine receptors (acetylcholine being the main neurotransmitter used by the parasympathetic nervous system). Atropine dilates the pupils, increases heart rate, and reduces salivation and other secretions [1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Autophagy >>AutophagySignaling Pathways >>GPCR/G Protein >>mAChRSignaling Pathways >>Neuronal Signaling >>mAChRResearch Areas >>Neurological DiseaseNatural Products >>Alkaloid |
| References | [1]. http://en.wikipedia.org/wiki/Atropine |
Chemical & Physical Properties
| Boiling Point | 429.8ºC at 760mmHg |
|---|---|
| Melting Point | 189-192 °C (A)(lit.) |
| Molecular Formula | C17H25NO7S |
| Molecular Weight | 387.45 |
| Flash Point | 213.7ºC |
| PSA | 191.75000 |
| LogP | 4.10130 |
| InChIKey | JPKKQJKQTPNWTR-BRYCGAMXSA-N |
| SMILES | CN1C2CCC1CC(OC(=O)C(CO)c1ccccc1)C2.CN1C2CCC1CC(OC(=O)C(CO)c1ccccc1)C2.O.O=S(=O)(O)O |
| Water Solubility | soluble |
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H300 + H330 |
| Precautionary Statements | P260-P264-P284-P301 + P310-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T+:Verytoxic; |
| Risk Phrases | R26/28;R36/37/38;R43 |
| Safety Phrases | S23-S45-S36/37/39-S26-S1 |
| RIDADR | UN 1544 6.1/PG 2 |
| WGK Germany | 2 |
| RTECS | CK2455000 |
| Packaging Group | II |
| Hazard Class | 6.1 |
| HS Code | 29399900 |
Customs
| HS Code | 29399900 |
|---|
Articles65
More Articles| The in vitro and in vivo profile of aclidinium bromide in comparison with glycopyrronium bromide. Pulm. Pharmacol. Ther. 28(2) , 114-21, (2014) This study characterised the in vitro and in vivo profiles of two novel long-acting muscarinic antagonists, aclidinium bromide and glycopyrronium bromide, using tiotropium bromide and ipratropium brom... | |
| The application of 1,8-cineole, a terpenoid oxide present in medicinal plants, inhibits castor oil-induced diarrhea in rats. Pharm. Biol. 53(4) , 594-9, (2015) 1,8-Cineole, a terpene, characterized as a major constituent occurring in the essential oils of several aromatic plants. It is widely used in pharmaceutical industry, as a food additive and for culina... | |
| Vasorelaxant activities of Danhong injection and their differential effects on the rat abdominal aorta and mesenteric artery. J. Cardiovasc. Pharmacol. 65(1) , 62-71, (2015) Previous studies have found that Danhong injection (DHI), an extensively used herbal extract preparation in China, might be a powerful vasodilator. The aims of this study were to determine the vascula... |
Synonyms
| MFCD00074815 |
| AtropineSulphateGrPuriss |
| Atropina Solfato |
| racemic anisodamine |
| atropine sulphate |
| atropin sulfate |
| Atropsiol |
| AtropineSulfat |
| TROPINI SULFAS |
| ATROPINI SULFAS |
| Atropt |
| Atropinsulfat |
| EINECS 200-235-0 |
