CAS 118-48-9|Isatoic anhydride
Introduction：Basic information about CAS 118-48-9|Isatoic anhydride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Isatoic anhydride | ||
|---|---|---|---|
| CAS Number | 118-48-9 | Molecular Weight | 163.130 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
| Molecular Formula | C8H5NO3 | Melting Point | 233 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 308 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 4H-3,1-Benzoxazine-2,4(1H)-dione |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Melting Point | 233 °C (dec.)(lit.) |
| Molecular Formula | C8H5NO3 |
| Molecular Weight | 163.130 |
| Flash Point | 308 °C |
| Exact Mass | 163.026947 |
| PSA | 63.07000 |
| LogP | 0.90 |
| Vapour density | 5.6 (vs air) |
| Index of Refraction | 1.586 |
| InChIKey | TXJUTRJFNRYTHH-UHFFFAOYSA-N |
| SMILES | O=c1[nH]c2ccccc2c(=O)o1 |
| Water Solubility | decomposes |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 34800 mg/kg
- SEX/DURATION :
- male 8 day(s) pre-mating female 21 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 15,7,1966
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317-H319 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36;R43 |
| Safety Phrases | S24-S26-S37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | DM3100000 |
| HS Code | 2934999090 |
Customs
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles16
More Articles| Hydrogen-bonding in 2-aminobenzoyl-alpha-chymotrypsin formed by acylation of the enzyme with isatoic anhydride: IR and mass spectroscopic studies. ChemBioChem. 3(1) , 68-75, (2002) The acyl-enzyme formed upon acylation of alpha-chymotrypsin with isatoic anhydride has been characterised by infrared spectroscopy. Acylation at pH 7 to yield the 2-aminobenzoyl-enzyme is rapid (k = 5... | |
| Palladium-catalyzed decarboxylative coupling of isatoic anhydrides with arylboronic acids. Org. Lett. 13 , 6114-6117, (2011) The decarboxylative coupling of isatoic anhydrides with arylboronic acids was realized for the first time in the presence of Pd(2)(dba)(3) and DPEphos, achieving aryl o-aminobenzoates with yields rang... | |
| 1,3-Dipolar cycloaddition-decarboxylation reactions of an azomethine ylide with isatoic anhydrides: formation of novel benzodiazepinones. Org. Lett. 13(3) , 486-9, (2011) A nonstabilized azomethine ylide reacts with a wide range of substituted isatoic anhydrides to afford novel 1,3-benzodiazepin-5-one derivatives, which are generally isolated in high yield. The transfo... |
Synonyms
| 2H-3,1-Benzoxazine-2,4(1H)-dione |
| Anthranilic acid N-carboxylic acid anhydride |
| Isatoic anhydride |
| 3,1-Benzoxazine-2,4(1H)-dione |
| 1H-3,1-benzoxazine-2,4-dione |
| 1H-Benzo[d][1,3]oxazine-2,4-dione |
| Isatoic acid anhydride |
| T66 BMVOVJ |
| Benzoic acid, 2-(carboxyamino)-, cyclic anhydride |
| Benzoxazinedione |
| Anthranilic acid, N-carboxy-, cyclic anhydride |
| MFCD00006700 |
| EINECS 204-255-0 |
