Introduction：Basic information about CAS 127408-31-5|Y-26763, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Y-26763 |
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| CAS Number | 127408-31-5 | Molecular Weight | 276.29 |
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| Density | 1.36g/cm3 | Boiling Point | 455.4ºC at 760mmHg |
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| Molecular Formula | C14H16N2O4 | Melting Point | / |
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| MSDS | / | Flash Point | 229.2ºC |
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Names
| Name | N-[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-N-hydroxyacetamide |
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| Synonym | More Synonyms |
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Y-26763 BiologicalActivity
| Description | Y-26763 is a K+ channel opener and active metabolite of Y-27152[1]. Y-26763 is an ATP-sensitive K+ (KATP) channel activator[2]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel |
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| References | [1]. Itoh T, et al. Effects of a newly synthesized K+ channel opener, Y-26763, on noradrenaline-induced Ca2+ mobilization in smooth muscle of the rabbit mesenteric artery. Br J Pharmacol. 1994 Jan;111(1):165-72. [2]. Tran QTN, et al. The identification of naturally occurring labdane diterpenoid calcaratarin D as a potential anti-inflammatory agent. Eur J Med Chem. 2019 Jul 15;174:33-44. |
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Chemical & Physical Properties
| Density | 1.36g/cm3 |
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| Boiling Point | 455.4ºC at 760mmHg |
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| Molecular Formula | C14H16N2O4 |
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| Molecular Weight | 276.29 |
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| Flash Point | 229.2ºC |
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| Exact Mass | 276.11100 |
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| PSA | 93.79000 |
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| LogP | 1.36898 |
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| Vapour Pressure | 4.4E-09mmHg at 25°C |
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| Index of Refraction | 1.615 |
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| InChIKey | IWTCFIIOUXJOOV-OLZOCXBDSA-N |
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| SMILES | CC(=O)N(O)C1c2cc(C#N)ccc2OC(C)(C)C1O |
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| Storage condition | 2-8℃ |
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Synonyms
