CAS 14215-68-0|N-Acetyl-D-galactosamine

Introduction：Basic information about CAS 14215-68-0|N-Acetyl-D-galactosamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. N-Acetyl-D-galactosamine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	N-Acetyl-D-galactosamine
CAS Number	14215-68-0	Molecular Weight	221.208
Density	1.5±0.1 g/cm3	Boiling Point	595.4±50.0 °C at 760 mmHg
Molecular Formula	C₈H₁₅NO₆	Melting Point	158-162 °C
MSDS	Chinese	Flash Point	313.9±30.1 °C

Names

Name	N-acetyl-D-galactosamine
Synonym	More Synonyms

N-Acetyl-D-galactosamine BiologicalActivity

Description	N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets[1].N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin[2].
Related Catalog	Research Areas >>Others
In Vitro	N-Acetyl-D-galactosamine (GalNAc) (50nm; 4 hours) decreases the expression of occludin mRNA and claudin-3 mRNA by 1.6% and 2.7%[1]. N-Acetyl-D-galactosamine (GalNAc) (50nm; 4 hours) lowers the protein expression of occludin and claudin-3 by 4.3% and 7.2%, respectively[1]. RT-PCR[1] Cell Line: IPEC-J2 cell Concentration: 50 nM Incubation Time: 4 hours Result: Observed a slight reduction in mRNA expression of occludin and claudin-3. Western Blot Analysis[1] Cell Line: IPEC-J2 cell Concentration: 50 nM Incubation Time: 4 hours Result: Alleviated the damage of tight junction expressions at protein level.
References	[1]. Zhao B, et al. N-Acetyl-d-galactosamine prevents soya bean agglutinin-induced intestinal barrier dysfunction in intestinal porcine epithelial cells. J Anim Physiol Anim Nutr (Berl). 2019 Jul;103(4):1198-1206. [2]. Sadanandan R, et al. Isolation, Purification and Characterisation of a D-galactose and N-acetyl-D-galactosamineSpecific Lectin from Marine Sponge Fasciospongia cavernosa. Protein Pept Lett. 2018;25(9):871-877.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	595.4±50.0 °C at 760 mmHg
Melting Point	158-162 °C
Molecular Formula	C₈H₁₅NO₆
Molecular Weight	221.208
Flash Point	313.9±30.1 °C
Exact Mass	221.089935
PSA	119.25000
LogP	-2.48
Vapour Pressure	0.0±3.8 mmHg at 25°C
Index of Refraction	1.576
InChIKey	OVRNDRQMDRJTHS-CBQIKETKSA-N
SMILES	CC(=O)NC1C(O)OC(CO)C(O)C1O
Storage condition	2~8°C

Safety Information

Hazard Codes	Xi: Irritant;
Safety Phrases	S22-S24/25
WGK Germany	3

Synonyms

N-[(3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl]acetamide

EINECS 217-321-9

MFCD00065372

D-Galactopyranose, 2-(acetylamino)-2-deoxy-

N-ACETEYL-D-GALACTOSAMINIDE

N-Acetyl-D-galactosamine

2-(Acetylamino)-2-deoxy-D-galactopyranose

N-acelyl-D-glucosamine

2-Acetamido-2-deoxy-D-galactose

N-Acetylchondrosamine

N-ACETYL-D-GALACTOSAMINIDE

N-((3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide

2-Acetamido-2-deoxy-D-galactopyranose Hydrate

2-Acetamido-2-deoxy-D-galactopyranose

ACETYL-D-GALACTOSAMINE

N-Acetyl-D-chondrosamine Hydrate

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