CAS 67306-00-7|Fenpropidin
| Common Name | Fenpropidin | ||
|---|---|---|---|
| CAS Number | 67306-00-7 | Molecular Weight | 273.45600 |
| Density | 0.924 g/cm3 | Boiling Point | 368.9ºC at 760 mmHg |
| Molecular Formula | C19H31N | Melting Point | 25°C |
| MSDS | ChineseUSA | Flash Point | 159.3ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine |
|---|---|
| Synonym | More Synonyms |
Fenpropidin BiologicalActivity
| Description | Fenpropidin is a sterol biosynthesis inhibitor fungicide[1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal |
| References | [1]. Ignaz J Buerge, et al. Stereoselective Metabolism of the Sterol Biosynthesis Inhibitor Fungicides Fenpropidin, Fenpropimorph, and Spiroxamine in Grapes, Sugar Beets, and Wheat. J Agric Food Chem. 2016 Jul 6;64(26):5301-9. |
Chemical & Physical Properties
| Density | 0.924 g/cm3 |
|---|---|
| Boiling Point | 368.9ºC at 760 mmHg |
| Melting Point | 25°C |
| Molecular Formula | C19H31N |
| Molecular Weight | 273.45600 |
| Flash Point | 159.3ºC |
| Exact Mass | 273.24600 |
| PSA | 3.24000 |
| LogP | 4.58650 |
| Index of Refraction | 1.507 |
| InChIKey | MGNFYQILYYYUBS-UHFFFAOYSA-N |
| SMILES | CC(Cc1ccc(C(C)(C)C)cc1)CN1CCCCC1 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1447 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(254),33,1988
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1200 gm/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(252),15,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1820 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(254),33,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,378,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- 1900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,378,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Bird - domestic
- DOSE/DURATION :
- 369 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(254),33,1988
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H319 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R21/22;R36 |
| Safety Phrases | S26-S36/37 |
| RIDADR | UN 2902 |
| WGK Germany | 3.0 |
| RTECS | TM7292000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 29333990 |
Articles10
More Articles| Investigations into the source of two fungicides measured in the air for 24 hours following application to a cereal crop. Commun. Agric. Appl. Biol. Sci. 74(1) , 37-46, (2009) Airborne pesticides can be detected near to recently-treated arable fields for a period of days following the application. Identifying the source of such pesticides is important in developing predicti... | |
| Inhibition of microbial cholesterol oxidases by dimethylmorpholines. J. Steroid Biochem. 35(1) , 107-13, (1990) Cholesterol oxidase is a potentially important enzyme in steroid transformations, catalysing the conversion of 3-hydroxy-5-ene steroids to 3-keto-4-ene derivatives via a 3-keto-5-ene intermediate. Mor... | |
| A sterol C-14 reductase encoded by FgERG24B is responsible for the intrinsic resistance of Fusarium graminearum to amine fungicides. Microbiology 157(Pt 6) , 1665-75, (2011) Fusarium graminearum, the causal agent of wheat head blight, shows intrinsic resistance to amine fungicides. It is commonly accepted that the amines target sterol C-14 reductase and sterol Δ(8)-Δ(7) i... |
Synonyms
| Ro 12-3049 |
| 1-(4-tert-butyl-phenyl)-3-piperidino-2-methyl-propane |
| N-[3-(p-tert-butylphenyl)-2-methylpropyl]-piperidine |
| Fenpropidine |
| fenpropidin |
| Patrol |
| 1-[3-(p-tert-butyl-phenyl)-2-methyl-propyl]-piperidine |
| 1-[3-[4-(1,1-dimethylethyl)phenyl]-2-methylpropyl]piperidine |
| 1-[(RS)-3-(4-tert-butylphenyl)-2-methylpropyl]piperidine |
| 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine |
| Fenpropidin [BSI:ISO] |
| Fenpropidin |
| rac-1-[(2R)-3-(4-tert-butylphenyl)-2-methylpropyl]piperidine |
| Fenpropidine [ISO-French] |
