CAS 14913-33-8|trans-Dichlorodiamineplatinum(II)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

TP2455000

CHEMICAL NAME :

Platinum (II), diamminedichloro-, trans-

CAS REGISTRY NUMBER :

14913-33-8

LAST UPDATED :

199709

DATA ITEMS CITED :

28

MOLECULAR FORMULA :

Cl2-H6-N2-Pt

MOLECULAR WEIGHT :

300.07

WISWESSER LINE NOTATION :

.PT..ZH2.G2 -T

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

27 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

32408 ug/kg/10W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors

MUTATION DATA

TYPE OF TEST :

DNA adduct

TEST SYSTEM :

Mammal - species unspecified Lymphocyte

DOSE/DURATION :

50 umol/L

REFERENCE :

CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 10,27,1975

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