Introduction：Basic information about CAS 21668-77-9|eprodisate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | eprodisate |
|---|
| CAS Number | 21668-77-9 | Molecular Weight | 204.222 |
|---|
| Density | 1.8±0.1 g/cm3 | Boiling Point | / |
|---|
| Molecular Formula | C3H8O6S2 | Melting Point | 120-124ºC |
|---|
| MSDS | ChineseUSA | Flash Point | / |
|---|
| Symbol |
GHS05, GHS07 | Signal Word | Danger |
|---|
Names
| Name | propane-1,3-disulfonic acid |
|---|
| Synonym | More Synonyms |
|---|
eprodisate BiologicalActivity
| Description | Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues[1]. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis[2]. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
|---|
| References | [1]. Dember LM, et al. Eprodisate for the treatment of renal disease in AA amyloidosis. N Engl J Med. 2007 Jun 7;356(23):2349-60. [2]. Manenti L, et al. Eprodisate in amyloid A amyloidosis: a novel therapeutic approach? Expert Opin Pharmacother. 2008 Aug;9(12):2175-80. |
|---|
Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
|---|
| Melting Point | 120-124ºC |
|---|
| Molecular Formula | C3H8O6S2 |
|---|
| Molecular Weight | 204.222 |
|---|
| Exact Mass | 203.976227 |
|---|
| PSA | 125.50000 |
|---|
| LogP | -3.47 |
|---|
| Index of Refraction | 1.549 |
|---|
| InChIKey | MGNVWUDMMXZUDI-UHFFFAOYSA-N |
|---|
| SMILES | O=S(=O)(O)CCCS(=O)(=O)O |
|---|
Safety Information
| Symbol |
GHS05, GHS07 |
|---|
| Signal Word | Danger |
|---|
| Hazard Statements | H302 + H312 + H332-H314 |
|---|
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
|---|
| Hazard Codes | Xi: Irritant;C: Corrosive; |
|---|
| Risk Phrases | 36/37/38-34-20/21/22 |
|---|
| Safety Phrases | S26-S36-S45-S36/37/39-S27 |
|---|
| RIDADR | 3265 |
|---|
| WGK Germany | 3 |
|---|
| Packaging Group | III |
|---|
| Hazard Class | 8 |
|---|
| HS Code | 2904100000 |
|---|
Customs
| HS Code | 2904100000 |
|---|
| Summary | 2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
|---|
Synonyms
| propanedisulfonate |
| Propane-1,3-disulfonate |
| Eprodisate [INN] |
| eprodisate |
| 1.3-propanesultone |
| 1,3-propane sulfone |
| Propane-1,3-disulfonic acid |
| 1,3-propanedisulphonic acid |
| 1,3-Propanedisulfonic acid |
| 1,3-Propanedisulfonicacid |
| UNII-6QFP76V7S7 |
| P8454_ALDRICH |
| 1,3-Propane disulfonate |
| MFCD00191483 |
