CAS 267402-71-1|Myoseverin

Introduction:Basic information about CAS 267402-71-1|Myoseverin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMyoseverin
CAS Number267402-71-1Molecular Weight432.518
Density1.2±0.1 g/cm3Boiling Point661.3±65.0 °C at 760 mmHg
Molecular FormulaC24H28N6O2Melting Point108 °C
MSDS/Flash Point353.7±34.3 °C

Names

Name2-N,6-N-bis[(4-methoxyphenyl)methyl]-9-propan-2-ylpurine-2,6-diamine
SynonymMore Synonyms

Myoseverin BiologicalActivity

DescriptionMyoseverina, a microtubule-binding molecule, induces the reversible fission of multinucleated myotubes into mononucleated fragments. Myoseverina affects the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and stress response genes, consistent with the activation of pathways involved in wound healing and tissue regeneration[1].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>Microtubule/TubulinResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Cytoskeleton >>Microtubule/Tubulin
References

[1]. Rosania GR, et al. Myoseverin, a microtubule-binding molecule with novel cellular effects. Nat Biotechnol. 2000;18(3):304-308.

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point661.3±65.0 °C at 760 mmHg
Melting Point108 °C
Molecular FormulaC24H28N6O2
Molecular Weight432.518
Flash Point353.7±34.3 °C
Exact Mass432.227386
PSA86.12000
LogP3.04
Vapour Pressure0.0±2.0 mmHg at 25°C
Index of Refraction1.632
InChIKeyIDCOTQWQVPRTNK-UHFFFAOYSA-N
SMILESCOc1ccc(CNc2nc(NCc3ccc(OC)cc3)c3ncn(C(C)C)c3n2)cc1

Safety Information

WGK Germany3

Synonyms

9H-Purine-2,6-diamine, N,N-bis[(4-methoxyphenyl)methyl]-9-(1-methylethyl)-
9-Isopropyl-N,N'-bis(4-methoxybenzyl)-9H-purine-2,6-diamine
myoseverin
n,n'-bis(4-methoxybenzyl)-9-(propan-2-yl)-9h-purine-2,6-diamine
9-Isoproyl-N2,N6-bis-(4-methoxybenxyl)-9H-purine-2,6-diamine
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