CAS 591-59-3|DL-Glyceraldehyde 3-phosphate
| Common Name | DL-Glyceraldehyde 3-phosphate | ||
|---|---|---|---|
| CAS Number | 591-59-3 | Molecular Weight | 170.05800 |
| Density | 1.721g/cm3 | Boiling Point | 399.2ºC at 760mmHg |
| Molecular Formula | C3H7O6P | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 195.2ºC |
| Symbol | GHS05 | Signal Word | Danger |
Names
| Name | DL-Glyceraldehyde 3-phosphate |
|---|---|
| Synonym | More Synonyms |
DL-Glyceraldehyde 3-phosphate BiologicalActivity
| Description | DL-Glyceraldehyde 3-phosphate is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. DL-Glyceraldehyde 3-phosphate is a potent inhibitor of the growth of E. coli. DL-Glyceraldehyde 3-phosphate is a competitive inhibitor of the acyltransferase[1][2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionResearch Areas >>Metabolic DiseaseSignaling Pathways >>Anti-infection >>Bacterial |
| In Vitro | DL-Glyceraldehyde 3-phosphate is a time-dependent inhibitor of the cationic and anionic isozymes of aspartate aminotransferase purified from rat liver[1]. DL-Glyceraldehyde 3-phosphate, an analogue of Glycerol 3-phosphate, enters the cell via the sn-glycerol 3-phosphate transport system and is bactericidal. DL-Glyceraldehyde 3-phosphate is an inhibitor of sn-glycerol 3-phosphate transport[2]. |
| In Vivo | In vivo, phosphatidylethanolamine and phosphatidylglycerol accumulation are inhibited to the same extent by the addition of DL-Glyceraldehyde 3-phosphate to a culture of E. coli[2]. |
| References | [1]. L Kopelovich, et al. Kinetics of the inhibition of aspartate aminotransferase isozymes by DL-glyceraldehyde 3-phosphate. Eur J Biochem. 1971 Jun 11;20(3):351-62. [2]. C T Tang, et al. L-Glyceraldehude 3-phosphate, a bactericidal agent. Antimicrob Agents Chemother. 1977 Jan;11(1):147-53. |
Chemical & Physical Properties
| Density | 1.721g/cm3 |
|---|---|
| Boiling Point | 399.2ºC at 760mmHg |
| Molecular Formula | C3H7O6P |
| Molecular Weight | 170.05800 |
| Flash Point | 195.2ºC |
| Exact Mass | 169.99800 |
| PSA | 113.87000 |
Safety Information
| Symbol | GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Risk Phrases | 34 |
| Safety Phrases | 26-27-36/37/39-45 |
| RIDADR | UN 1760 8/PG 2 |
| Packaging Group | II |
Articles1593
More Articles| Gene transfer of high-mobility group box 1 box-A domain in a rat acute liver failure model. J. Surg. Res. 194(2) , 571-80, (2015) High-mobility group box 1 (HMGB1) has recently been identified as an important mediator of various kinds of acute and chronic inflammation. The protein encoded by the box-A domain of the HMGB1 gene is... | |
| MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes. Arthritis. Res. Ther. 17 , 42, (2015) Several studies have shown that osteoarthritis (OA) is strongly associated with metabolism-related disorders, highlighting OA as the fifth component of the metabolic syndrome (MetS). On the basis of o... | |
| Intraplacental gene therapy with Ad-IGF-1 corrects naturally occurring rabbit model of intrauterine growth restriction. Hum. Gene Ther. 26(3) , 172-82, (2015) Intrauterine growth restriction (IUGR) due to placental insufficiency is a leading cause of perinatal complications for which there is no effective prenatal therapy. We have previously demonstrated th... |
Synonyms
| dl-glyceraldehyde 3-phosphate |
