CAS 59481-27-5|[Tyr11]-Somatostatin
Introduction：Basic information about CAS 59481-27-5|[Tyr11]-Somatostatin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | [Tyr11]-Somatostatin | ||
|---|---|---|---|
| CAS Number | 59481-27-5 | Molecular Weight | 1653.878 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 2000.6±65.0 °C at 760 mmHg |
| Molecular Formula | C76H104N18O20S2 | Melting Point | / |
| MSDS | / | Flash Point | 1163.7±34.3 °C |
Names
| Name | L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-25,28-dibenzyl-4-carboxy-13-(4-hydroxybenzyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide |
|---|---|
| Synonym | More Synonyms |
[Tyr11]-Somatostatin BiologicalActivity
| Description | [Tyr11]-Somatostatin is a neuroavtive peptide for proteomics research. Somatostatin is one of many neuroactive substances that influence retinal physiology[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
| In Vitro | Iodination of [Tyr11]-Somatostatin yields a super high affinity ligand for somatostatin receptors in GH4C1 pituitary cells[2]. |
| References | [1]. Vasilaki A, et al. Somatostatin mediates nitric oxide production by activating sst(2) receptors in the rat retina. Neuropharmacology. 2002;43(5):899-909. [2]. Presky DH, Schonbrunn A. Iodination of [Tyr11]somatostatin yields a super high affinity ligand for somatostatin receptors in GH4C1 pituitary cells. Mol Pharmacol. 1988;34(5):651-658. |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 2000.6±65.0 °C at 760 mmHg |
| Molecular Formula | C76H104N18O20S2 |
| Molecular Weight | 1653.878 |
| Flash Point | 1163.7±34.3 °C |
| Exact Mass | 1652.711548 |
| PSA | 684.06000 |
| LogP | -4.99 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.676 |
| InChIKey | BANSKZGUYZBDPC-GWVZWCPESA-N |
| SMILES | CC(N)C(=O)NCC(=O)NC1CSSCC(C(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(C(C)O)NC(=O)C(CCCCN)NC(=O)C(Cc2cc3ccccc3[nH]2)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2ccccc2)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC1=O |
Synonyms
| Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Tyr-Thr-Ser-Cys |
| L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-25,28-dibenzyl-4-carboxy-13-(4-hydroxybenzyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide |
| Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-13-[(4-hydroxyphenyl)methyl]-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-25,28-bis(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]- |
| (Tyr11)-Somatostatin-14 |
