CAS 59530-69-7|(Leu13)-Motilin (human, porcine) trifluoroacetate salt

Introduction:Basic information about CAS 59530-69-7|(Leu13)-Motilin (human, porcine) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(Leu13)-Motilin (human, porcine) trifluoroacetate salt
CAS Number59530-69-7Molecular Weight2681.01
Density/Boiling Point/
Molecular FormulaC121H190N34O35Melting Point/
MSDS/Flash Point/

Names

Name13-Leu-motilin
SynonymMore Synonyms

BiologicalActivity

Description[Leu13]-Motilin (KW-5139) is a motilin analogue. [Leu13]-Motilin stimulates gastrointestinal motility in the rabbit. [Leu13]-Motilin causes concentration-dependent contractions of the gastric antrum, duodenum, jejunum, ileum and the descending colon in vitro[1].
Related CatalogResearch Areas >>Metabolic DiseaseSignaling Pathways >>GPCR/G Protein >>Motilin Receptor
References

[1]. Kitazawa T, et al. Stimulating action of KW-5139 (Leu13-motilin) on gastrointestinal motility in the rabbit. Br J Pharmacol. 1994 Jan;111(1):288-94.

Chemical & Physical Properties

Molecular FormulaC121H190N34O35
Molecular Weight2681.01
Exact Mass2679.41000
PSA1166.19000
LogP5.04760
InChIKeyGFOZQXMKARUPQI-DFIBRNPJSA-N
SMILESCCC(C)C(NC(=O)C1CCCN1C(=O)C(NC(=O)C(N)Cc1ccccc1)C(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(N)=O)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)O)C(C)O

Synonyms

kw 5139
(Leu13)-Motilin
[Leu13]-Motilin
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