Introduction：Basic information about CAS 59989-18-3|Eniluracil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Eniluracil |
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| CAS Number | 59989-18-3 | Molecular Weight | 136.10800 |
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| Density | 1.39g/cm3 | Boiling Point | / |
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| Molecular Formula | C6H4N2O2 | Melting Point | 320 °C(dec.) |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-ethynyl-1H-pyrimidine-2,4-dione |
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| Synonym | More Synonyms |
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Eniluracil BiologicalActivity
| Description | Eniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| Target | Dihydropyrimidine dehydrogenase[1] |
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| References | [1]. Schilsky RL, et al. Eniluracil: an irreversible inhibitor of dihydropyrimidine dehydrogenase. Expert Opin Investig Drugs. 2000 Jul;9(7):1635-49. |
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Chemical & Physical Properties
| Density | 1.39g/cm3 |
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| Melting Point | 320 °C(dec.) |
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| Molecular Formula | C6H4N2O2 |
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| Molecular Weight | 136.10800 |
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| Exact Mass | 136.02700 |
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| PSA | 65.72000 |
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| Index of Refraction | 1.589 |
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| InChIKey | JOZGNYDSEBIJDH-UHFFFAOYSA-N |
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| SMILES | C#Cc1c[nH]c(=O)[nH]c1=O |
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Synonyms
| ethynyluracil |
| 5-ETHYNYLURACIL |
| Compound 776C |
| Eniluracil |
| ethynyluracyl |
| GW776C85 |
| 776C85 |
