Introduction：Basic information about CAS 80134-83-4|L-Leucine-1-13C,15N, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | L-Leucine-1-13C,15N |
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| CAS Number | 80134-83-4 | Molecular Weight | 133.15900 |
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| Density | 1.035 g/cm3 | Boiling Point | / |
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| Molecular Formula | C513CH1315NO2 | Melting Point | >300ºC(lit.) |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | L-Leucine-1-13C,15N |
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| Synonym | More Synonyms |
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L-Leucine-1-13C,15N BiologicalActivity
| Description | L-Leucine-1-13C,15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. |
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| Related Catalog | Signaling Pathways >>PI3K/Akt/mTOR >>mTORResearch Areas >>Metabolic Disease |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |
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Chemical & Physical Properties
| Density | 1.035 g/cm3 |
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| Melting Point | >300ºC(lit.) |
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| Molecular Formula | C513CH1315NO2 |
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| Molecular Weight | 133.15900 |
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| Exact Mass | 133.09500 |
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| PSA | 63.32000 |
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| LogP | 1.14470 |
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| InChIKey | ROHFNLRQFUQHCH-XAAHKOKXSA-N |
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| SMILES | CC(C)CC(N)C(=O)O |
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Safety Information
| RIDADR | NONH for all modes of transport |
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Synonyms
| L-leucine-1-(13)C-(15)N |
| MFCD04113750 |
