CAS 80483-89-2|Isohomobrassinolide
| Common Name | Isohomobrassinolide | ||
|---|---|---|---|
| CAS Number | 80483-89-2 | Molecular Weight | 494.704 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 643.0±55.0 °C at 760 mmHg |
| Molecular Formula | C29H50O6 | Melting Point | 193-194ºC |
| MSDS | ChineseUSA | Flash Point | 203.2±25.0 °C |
Names
| Name | (2R,3S,22S,24S)-2,3,22,23-TETRAHYDROXY-24-ETHYL-β-HOMO-7-OXA-5A-CHOLESTAN-6-ONE |
|---|---|
| Synonym | More Synonyms |
Isohomobrassinolide BiologicalActivity
| Description | (22S,23S)-Homobrassinolide is one of the most active brassinosteroids in inducing plant growth in various plant bioassay systems. (22S,23S)-Homobrassinolide shows Akt-dependent anabolic activity in rat skeletal muscle cells. Orally active[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
| In Vitro | (22S,23S)-Homobrassinolide slightly stimulates ferricyanide reduction and promotes uptake of sucrose and alpha-aminoisobutyric acid [2]. |
| References | [1]. Esposito D, et al. Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells. J Med Chem. 2011;54(12):4057-4066. [2]. Dahse I, et al. Effects of (22S,23S)-Homobrassinolide and Related Compounds on Membrane Potential and Transport of Egeria Leaf Cells. Plant Physiol. 1990;93(3):1268-1271. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 643.0±55.0 °C at 760 mmHg |
| Melting Point | 193-194ºC |
| Molecular Formula | C29H50O6 |
| Molecular Weight | 494.704 |
| Flash Point | 203.2±25.0 °C |
| Exact Mass | 494.360748 |
| PSA | 107.22000 |
| LogP | 3.65 |
| Vapour Pressure | 0.0±4.3 mmHg at 25°C |
| Index of Refraction | 1.533 |
| InChIKey | HJIKODJJEORHMZ-DNVPGCTHSA-N |
| SMILES | CCC(C(C)C)C(O)C(O)C(C)C1CCC2C3COC(=O)C4CC(O)C(O)CC4(C)C3CCC12C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles27
More Articles| Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells. J. Med. Chem. 54 , 4057-4066, (2011) Brassinosteroids are plant-derived polyhydroxylated derivatives of 5α-cholestane, structurally similar to cholesterol-derived animal steroid hormones and insect ecdysteroids. In this study, we synthes... | |
| Brassinosteroids protect Lycopersicon esculentum from cadmium toxicity applied as shotgun approach. Protoplasma 239(1-4) , 3-14, (2010) Surface-sterilized seeds of two tomato cultivars (cv. K-25 and Sarvodya) were soaked in 100 microM CdCl(2) for 8 h (shotgun approach). The resulting 59-day-old seedlings were sprayed with 10(-8) M of ... | |
| Synthesis and bioactivity of natural and C-3 fluorinated biosynthetic precursors of 28-homobrassinolide. Phytochemistry 58(6) , 973-80, (2001) In this paper we describe the synthesis of two new fluorinated brassinosteroids: (22R,23R)-22,23-dihydroxy-3alpha-fluorostigmastan-6-one and (22R,23R)-22,23-dihydroxy-3beta-fluorostigmastan-6-one. The... |
Synonyms
| Cholest-5-ene-3|A,22-diol |
| 22R-hydroxycholesterol |
| (22R)-22-hydroxycholesterol |
| cholest-5-en-3beta,22-diol |
| 22S,23S-28-homobrassinolide |
| 22S,23S-homobrassinolide |
| 22(S)-hydroxycholesterol |
| 3H-Benz[c]indeno[5,4-e]oxepin-3-one, 10-[(1S,2S,3S,4S)-4-ethyl-2,3-dihydroxy-1,5-dimethylhexyl]hexadecahydro-5,6-dihydroxy-7a,9a-dimethyl-, (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)- |
| Cholest-5-ene-3beta,22-diol |
| (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)-10-[(2S,3S,4S,5S)-5-Ethyl-3,4-dihydroxy-6-methyl-2-heptanyl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one |
| 22-Hydroxycholesterol |
| (22S)-22-Hydroxycholesterol |
| Isohomobrassinolide |
