CAS 80508-23-2|rac N'-Nitrosonornicotine
| Common Name | rac N'-Nitrosonornicotine | ||
|---|---|---|---|
| CAS Number | 80508-23-2 | Molecular Weight | 177.20300 |
| Density | / | Boiling Point | 154ºC at 0.2 MM HG |
| Molecular Formula | C9H11N3O | Melting Point | 43-45ºC |
| MSDS | ChineseUSA | Flash Point | 9℃ |
| Symbol | GHS06, GHS08 | Signal Word | Danger |
Names
| Name | nnn 100 ug/ml in nonane:ethanol (9:1) |
|---|---|
| Synonym | More Synonyms |
rac N'-Nitrosonornicotine BiologicalActivity
| Description | 3-(1-Nitrosopyrrolidin-2-yl)pyridine is a major tobacco-specific nitrosamine[1]. |
|---|---|
| Related Catalog | Research Areas >>Others |
| References | [1]. Gao Y, Miksys S, Palmour RM, Tyndale RF. The Influence of Tobacco Smoke/Nicotine on CYP2A Expression in Human and African Green Monkey Lungs. Mol Pharmacol. 2020;98(6):658-668. |
Chemical & Physical Properties
| Boiling Point | 154ºC at 0.2 MM HG |
|---|---|
| Melting Point | 43-45ºC |
| Molecular Formula | C9H11N3O |
| Molecular Weight | 177.20300 |
| Flash Point | 9℃ |
| Exact Mass | 177.09000 |
| PSA | 45.56000 |
| LogP | 1.83780 |
| InChIKey | XKABJYQDMJTNGQ-UHFFFAOYSA-N |
| SMILES | O=NN1CCCC1c1cccnc1 |
| Storage condition | -20°C Freezer |
Safety Information
| Symbol | GHS06, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H351 |
| Precautionary Statements | P281-P301 + P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | F,T |
| Risk Phrases | 25-40-39/23/24/25-23/24/25-11 |
| Safety Phrases | 36/37-45-16 |
| RIDADR | UN2811 6.1/PG 3 |
Articles34
More Articles| Genome-wide analysis of DNA methylation dynamics during early human development. PLoS Genet. 10(12) , e1004868, (2014) DNA methylation is globally reprogrammed during mammalian preimplantation development, which is critical for normal development. Recent reduced representation bisulfite sequencing (RRBS) studies sugge... | |
| Tobacco-specific N-nitrosamine exposures and cancer risk in the Shanghai Cohort Study: remarkable coherence with rat tumor sites. Int. J. Cancer 134(10) , 2278-83, (2014) The tobacco-specific nitrosamines N'-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) are potent carcinogens for the rat esophagus and lung, respectively. Consistent w... | |
| Evidence supporting product standards for carcinogens in smokeless tobacco products. Cancer Prev. Res. (Phila.) 8(1) , 20-6, (2015) Smokeless tobacco products sold in the United States vary significantly in yields of nicotine and tobacco-specific nitrosamines (TSNA). With the passage of the Family Smoking Prevention and Tobacco Co... |
Synonyms
| [3H]-(+/-)-N'-Nitrosonornicotine |
| nitroso-propyl-carbamic acid ethyl ester |
| N-Propyl-N-nitrosourethane |
| N-nitroso-N-n-propylurethane |
| 3-(1-nitroso-pyrrolidin-2-yl)-pyridine |
| N-Propyl-N-nitrosourethan |
| N-Nitroso-N-propyl-urethan |
| CARBAMIC ACID,N-NITROSO-N-PROPYL-,ETHYL ESTER |
| 1'-nitroso-6'-nor-nicotine |
| Nitroso-propyl-carbamidsaeure-aethylester |
| N-nitrosonornicotine |
| N-Nitroso-nornicotin |
