Introduction：Basic information about CAS 155488-25-8|Sograzepide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sograzepide |
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| CAS Number | 155488-25-8 | Molecular Weight | 498.57600 |
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| Density | 1.25g/cm3 | Boiling Point | 723.049ºC at 760 mmHg |
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| Molecular Formula | C28H30N6O3 | Melting Point | / |
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| MSDS | / | Flash Point | 391.086ºC |
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Names
| Name | 1-[(3R)-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-5-pyridin-2-yl-3H-1,4-benzodiazepin-3-yl]-3-[3-(methylamino)phenyl]urea |
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| Synonym | More Synonyms |
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Sograzepide BiologicalActivity
| Description | Sograzepide (Netazepide;YF476) is a gastrin/cholecystokinin 2 receptor (CCK2) antagonist. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Cholecystokinin ReceptorResearch Areas >>Metabolic Disease |
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| Target | Gastrin/cholecystokinin 2 receptor (CCK2)[1] |
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| References | [1]. Boyce M, et al. Effect of netazepide, a gastrin/CCK2 receptor antagonist, on gastric acid secretion and rabeprazole-induced hypergastrinaemia in healthy subjects. Br J Clin Pharmacol. 2015 May;79(5):744-55. |
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Chemical & Physical Properties
| Density | 1.25g/cm3 |
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| Boiling Point | 723.049ºC at 760 mmHg |
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| Molecular Formula | C28H30N6O3 |
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| Molecular Weight | 498.57600 |
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| Flash Point | 391.086ºC |
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| Exact Mass | 498.23800 |
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| PSA | 119.28000 |
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| LogP | 4.04840 |
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| InChIKey | YDZYKNJZCVIKPP-VWLOTQADSA-N |
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| SMILES | CNc1cccc(NC(=O)NC2N=C(c3ccccn3)c3ccccc3N(CC(=O)C(C)(C)C)C2=O)c1 |
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| Storage condition | 2-8℃ |
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Synonyms
| UNII-HOU4I0G29C |
| YF-476 |
| Sograzepide |
