Introduction：Basic information about CAS 20636-48-0|Nonylbenzene-PEG5-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Nonylbenzene-PEG5-OH |
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| CAS Number | 20636-48-0 | Molecular Weight | 440.61300 |
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| Density | 1.016g/cm3 | Boiling Point | 541.2ºC at 760 mmHg |
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| Molecular Formula | C25H44O6 | Melting Point | / |
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| MSDS | / | Flash Point | 281.1ºC |
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Names
| Name | 2-[2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
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| Synonym | More Synonyms |
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Nonylbenzene-PEG5-OH BiologicalActivity
| Description | Nonylbenzene-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.016g/cm3 |
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| Boiling Point | 541.2ºC at 760 mmHg |
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| Molecular Formula | C25H44O6 |
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| Molecular Weight | 440.61300 |
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| Flash Point | 281.1ºC |
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| Exact Mass | 440.31400 |
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| PSA | 66.38000 |
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| LogP | 4.41720 |
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| Vapour Pressure | 1.52E-12mmHg at 25°C |
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| Index of Refraction | 1.489 |
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| InChIKey | PITRRWWILGYENJ-UHFFFAOYSA-N |
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| SMILES | CCCCCCCCCc1ccc(OCCOCCOCCOCCOCCO)cc1 |
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| Storage condition | 2-8°C |
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Safety Information
Customs
| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| polyoxyethylene(5) nonylphenyl ether |
| nonylphenol ethoxylate |
| Igepal CO-520 |
| 3,6,9,12-Tetraoxatetradecan-1-ol,14-(4-nonylphenoxy) |
| 4-nonylphenol pentaethoxylate |
