CAS 129280-33-7|Semilicoisoflavone B

Introduction：Basic information about CAS 129280-33-7|Semilicoisoflavone B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Semilicoisoflavone B BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Semilicoisoflavone B
CAS Number	129280-33-7	Molecular Weight	352.337
Density	1.4±0.1 g/cm3	Boiling Point	615.5±55.0 °C at 760 mmHg
Molecular Formula	C₂₀H₁₆O₆	Melting Point	/
MSDS	/	Flash Point	225.5±25.0 °C

Names

Name	semilicoisoflavone B
Synonym	More Synonyms

Semilicoisoflavone B BiologicalActivity

Description	Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation[1].
Related Catalog	Research Areas >>Neurological Disease
References	[1]. Gu MY, et al. Glycyrrhiza uralensis and Semilicoisoflavone B Reduce Aβ Secretion by Increasing PPARγ Expression and Inhibiting STAT3 Phosphorylation to Inhibit BACE1 Expression. Mol Nutr Food Res. 2018 Mar;62(6):e1700633.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	615.5±55.0 °C at 760 mmHg
Molecular Formula	C₂₀H₁₆O₆
Molecular Weight	352.337
Flash Point	225.5±25.0 °C
Exact Mass	352.094696
PSA	100.13000
LogP	4.48
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.683
InChIKey	LWZACZCRAUQSLH-UHFFFAOYSA-N
SMILES	CC1(C)C=Cc2cc(-c3coc4cc(O)cc(O)c4c3=O)cc(O)c2O1

Safety Information

Hazard Codes	Xi

Synonyms

4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-

SemilicoisoflavoneB

5,7-dihydroxy-3-(8-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one

5,7,8'-Trihydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one

Semilicoisoflavone B

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