Introduction：Basic information about CAS 840486-93-3|Adipiplon, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Adipiplon |
|---|
| CAS Number | 840486-93-3 | Molecular Weight | 351.38100 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C18H18FN7 | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | 7-[[2-(3-fluoropyridin-2-yl)imidazol-1-yl]methyl]-2-methyl-8-propyl-[1,2,4]triazolo[1,5-c]pyrimidine |
|---|
| Synonym | More Synonyms |
|---|
Adipiplon BiologicalActivity
| Description | Adipiplon (NG2-73) is a selective GABAA receptor positive allosteric modulator. Adipiplon is particularly useful in the treatment of a variety of central nervous system (CNS) disorders. |
|---|
| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>GABA Receptor |
|---|
| References | [1]. Vinkers CH, Olivier B, Hanania T, et al. Discriminative stimulus properties of GABAA receptor positive allosteric modulators TPA023, ocinaplon and NG2-73 in rats trained to discriminate chlordiazepoxide or zolpidem. Eur J Pharmacol. 2011;668(1-2):190-193. [2]. Xie, Linghong; Han, Bingsong; Xu, Yuelian. et al. Preparation of imidazo-pyrimidines and triazolo-pyrimidines as benzodiazepine receptor ligands for the treatment of central nervous system diseases. WO2005012306A2. |
|---|
Chemical & Physical Properties
| Molecular Formula | C18H18FN7 |
|---|
| Molecular Weight | 351.38100 |
|---|
| Exact Mass | 351.16100 |
|---|
| PSA | 73.79000 |
|---|
| LogP | 2.83110 |
|---|
| InChIKey | UAMAIHOEGLEXSV-UHFFFAOYSA-N |
|---|
| SMILES | CCCc1c(Cn2ccnc2-c2ncccc2F)ncn2nc(C)nc12 |
|---|
Synonyms
| NG2-73 |
| Apiplon |
| Adipiplon |
| UNII-OPL214POJ1 |
