Introduction：Basic information about CAS 142-28-9|1,3-Dichloropropane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1,3-Dichloropropane |
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| CAS Number | 142-28-9 | Molecular Weight | 112.986 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 120.4±0.0 °C at 760 mmHg |
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| Molecular Formula | C3H6Cl2 | Melting Point | −99 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 32.2±0.0 °C |
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| Symbol |
GHS02, GHS07 | Signal Word | Warning |
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Names
| Name | 1,3-Dichloropropane |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 120.4±0.0 °C at 760 mmHg |
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| Melting Point | −99 °C(lit.) |
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| Molecular Formula | C3H6Cl2 |
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| Molecular Weight | 112.986 |
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| Flash Point | 32.2±0.0 °C |
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| Exact Mass | 111.984657 |
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| LogP | 2.00 |
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| Vapour Pressure | 18.3±0.2 mmHg at 25°C |
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| Index of Refraction | 1.422 |
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| InChIKey | YHRUOJUYPBUZOS-UHFFFAOYSA-N |
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| SMILES | ClCCCCl |
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| Water Solubility | 0.8 g/L (20 ºC) |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TX9660000
- CHEMICAL NAME :
- Propane, 1,3-dichloro-
- CAS REGISTRY NUMBER :
- 142-28-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C3-H6-Cl2
- MOLECULAR WEIGHT :
- 112.99
- WISWESSER LINE NOTATION :
- G3G
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3600 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - ulceration or bleeding from stomach Gastrointestinal - ulceration or bleeding from small intestine
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - chronic pulmonary edema Liver - other changes Blood - hemorrhage
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8400 mg/kg/14D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Biochemical - Metabolism (Intermediary) - other proteins
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 72 gm/kg/90D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
MUTATION DATA - TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 6600 umol/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,401,1987
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Safety Information
| Symbol |
GHS02, GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H226-H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
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| Hazard Codes | F:Flammable |
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| Risk Phrases | R11;R20/22 |
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| Safety Phrases | S9-S16-S29-S33-S24-S61-S26-S45-S36/37-S7 |
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| RIDADR | UN 1993 3/PG 2 |
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| WGK Germany | 2 |
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| RTECS | TX9660000 |
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| Packaging Group | II |
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| Hazard Class | 3 |
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| HS Code | 2903199000 |
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Customs
| HS Code | 2903199000 |
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| Summary | 2903199000 other saturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
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Articles12
More Articles
| Metabolism and mutagenicity of source water contaminants 1,3-dichloropropane and 2,2-dichloropropane. Drug Metab. Dispos. 32(1) , 123-31, (2004) Cytochrome P450-dependent oxidation and glutathione (GSH)-dependent conjugation are the primary routes of metabolism of haloalkanes. Using rat liver microsomes and cytosol, we investigated the metabol... | |
| 1,3-Dichloropropene (technical grade). Rep. Carcinog. 10 , 91-3, (2002)
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| Biological effect monitoring. Arch. Toxicol. Suppl. 15 , 268-77, (1992)
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Synonyms
| Propandiyldichlorid |
| 1,3-dichloropropan-2-one O-benzyloxime |
| MFCD00000999 |
| 1,3-dichloro-2-propanone O-benzyloxime |
| EINECS 205-531-3 |
| 1,3-Dichlor-propan |
| 1,3-dichloro-propane |
| Propane, 1,3-dichloro- |
| 1,3-Dichloropropane |
| Trimethylene dichloride |
| 1,3-dichlorpropane |
| Trimethylene Chloride |
| 3-chloropropyl chloride |
