CAS 86-87-3|1-Naphthaleneacetic acid

Introduction:Basic information about CAS 86-87-3|1-Naphthaleneacetic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name1-Naphthaleneacetic acid
CAS Number86-87-3Molecular Weight186.207
Density1.2±0.1 g/cm3Boiling Point373.2±11.0 °C at 760 mmHg
Molecular FormulaC12H10O2Melting Point141-143 °C(lit.)
MSDSChineseUSAFlash Point270.1±14.4 °C
Symbol
GHS05, GHS07
Signal WordDanger

Names

Name1-naphthylacetic acid
SynonymMore Synonyms

1-Naphthaleneacetic acid BiologicalActivity

Description1-Naphthaleneacetic acid (NAA) is a synthetic plant growth regulator with auxin activity; can be added to cell culture media.
Related CatalogSignaling Pathways >>Others >>OthersBiochemical Assay ReagentsResearch Areas >>Others

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point373.2±11.0 °C at 760 mmHg
Melting Point141-143 °C(lit.)
Molecular FormulaC12H10O2
Molecular Weight186.207
Flash Point270.1±14.4 °C
Exact Mass186.068085
PSA37.30000
LogP2.74
Vapour Pressure0.0±0.9 mmHg at 25°C
Index of Refraction1.652
Water Solubilityacetone: 50 mg/mL, clear

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QJ0875000
CHEMICAL NAME :
1-Naphthaleneacetic acid
CAS REGISTRY NUMBER :
86-87-3
LAST UPDATED :
199710
DATA ITEMS CITED :
17
MOLECULAR FORMULA :
C12-H10-O2
MOLECULAR WEIGHT :
186.22
WISWESSER LINE NOTATION :
L66J B1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>207 gm/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
743 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
609 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
733 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
27 gm/kg/90D-C
TOXIC EFFECTS :
Behavioral - food intake (animal) Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
30 gm/kg/30D-I
TOXIC EFFECTS :
Liver - changes in liver weight Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Human Leukocyte
DOSE/DURATION :
100 nmol/L
REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 32,29,1976 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80317 No. of Facilities: 43 (estimated) No. of Industries: 1 No. of Occupations: 8 No. of Employees: 605 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80317 No. of Facilities: 287 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 3732 (estimated) No. of Female Employees: 574 (estimated)

Safety Information

Symbol
GHS05, GHS07
Signal WordDanger
Hazard StatementsH302-H315-H318-H335-H412
Precautionary StatementsP261-P273-P280-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXn:Harmful
Risk PhrasesR22
Safety PhrasesS26-S36-S24/25-S36/39-S22-S23
RIDADRNONH for all modes of transport
WGK Germany3
RTECSQJ0876000
HS Code2916399090

Customs

HS Code2916399090
Summary2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Synonyms

1-Naphthaleneacetic acid
L66J B1VQ
α-Naphthylacetic acid
α-NAA
Naphthalene-1-acetic acid
1-Naphthylacetic acid
Acetic acid, 1-naphthyl-
Naphthalen-1-ylacetic acid
α-Naphthaleneacetic acid
1-Naphthalene Acetic Acid
NAPHTHALENEACETIC ACID
2-(1-Naphthyl)acetic acid
1-NAA
EINECS 209-475-0
2-(α-Naphthyl)ethanoic acid
α-Naphthyleneacetic acid
MFCD00004126
Naphthaleneacetic acid (VAN)
1-NAPHTHYL ACETIC ACID
NAA
Naphazoline Impurity 2
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