CAS 2614-55-3|H-Ala-D-Glu(Lys-D-Ala-D-Ala-OH)-OH
| Common Name | H-Ala-D-Glu(Lys-D-Ala-D-Ala-OH)-OH | ||
|---|---|---|---|
| CAS Number | 2614-55-3 | Molecular Weight | 488.53500 |
| Density | / | Boiling Point | / |
| Molecular Formula | C20H36N6O8 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | 5-[[6-amino-1-[[1-(1-carboxyethylamino)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-2-(2-aminopropanoylamino)-5-oxopentanoic acid |
|---|---|
| Synonym | More Synonyms |
H-Ala-D-Glu(Lys-D-Ala-D-Ala-OH)-OH BiologicalActivity
| Description | Ala-D-γ-Glu-Lys-D-Ala-D-Ala is the pentapeptide tail of the peptidoglycan precursor UDPMurNAc-l-Ala-γ-d-Glu-l-Lys(Gly)(5)-d-Ala-d-Ala[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Tossavainen H, et al Structural and Functional Insights Into Lysostaphin-Substrate Interaction. Front Mol Biosci. 2018;5:60. Published 2018 Jul 3. |
Chemical & Physical Properties
| Molecular Formula | C20H36N6O8 |
|---|---|
| Molecular Weight | 488.53500 |
| Exact Mass | 488.25900 |
| PSA | 257.00000 |
| LogP | 2.15280 |
| InChIKey | MCIBYIIODNXVSL-MQLXINIDSA-N |
| SMILES | CC(N)C(=O)NC(CCC(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(C)C(=O)O)C(=O)O |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles12
More Articles| TMEFF2 deregulation contributes to gastric carcinogenesis and indicates poor survival outcome. Clin. Cancer Res. 20(17) , 4689-704, (2014) The role and clinical implication of the transmembrane protein with EGF and two follistatin motifs 2 (TMEFF2) in gastric cancer is poorly understood.Gene expression profile analyses were performed and... | |
| Synthesis of the L-alanyl-L-alanine cross-bridge of Enterococcus faecalis peptidoglycan. J. Biol. Chem. 277 , 45935-45941, (2002) The enzymatic synthesis of the complete l-alanyl(1)-l-alanine(2) side chain of the peptidoglycan precursors of Enterococcus faecalis was obtained in vitro using purified enzymes. The pathway involved ... | |
| Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins. Proc. Natl. Acad. Sci. U. S. A. 104 , 8761-8766, (2007) Peptidoglycan recognition proteins (PGRPs) are highly conserved pattern-recognition molecules of the innate immune system that bind bacterial peptidoglycans (PGNs), which are polymers of alternating N... |
Synonyms
| Peptidoglycan pentapeptide |
| Ala-D-|A-Glu-Lys-D-Ala-D-Ala |
| 5-[[6-amino-1-[[1-[(1-hydroxy-1-oxopropan-2-yl)amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-2-(2-aminopropanoylamino)-5-oxopentanoic acid |
