Introduction：Basic information about CAS 514-39-6|Periplogenin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Periplogenin |
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| CAS Number | 514-39-6 | Molecular Weight | 390.51300 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C23H34O5 | Melting Point | 245-248℃ |
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| MSDS | / | Flash Point | / |
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Names
| Name | 3-[(3S,5S,8R,9S,10R,13R,14S,17R)-3,5,14-trihydroxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one |
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| Synonym | More Synonyms |
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Periplogenin BiologicalActivity
| Description | Periplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots，with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Zhang WJ, et al. Periplogenin induces necroptotic cell death through oxidative stress in HaCaT cells and ameliorates skin lesions in the TPA- and IMQ-induced psoriasis-like mouse models. Biochem Pharmacol. 2016 Apr 1;105:66-79. [2]. Han HS, et al. Phellopterin isolated from Angelica dahurica reduces blood glucose level in diabetic mice. Heliyon. 2018 Mar; 4(3): e00577. |
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Chemical & Physical Properties
| Melting Point | 245-248℃ |
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| Molecular Formula | C23H34O5 |
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| Molecular Weight | 390.51300 |
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| Exact Mass | 390.24100 |
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| PSA | 86.99000 |
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| LogP | 2.71920 |
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| InChIKey | QJPCKAJTLHDNCS-FBAXFMHRSA-N |
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| SMILES | CC12CCC(O)CC1(O)CCC1C2CCC2(C)C(C3=CC(=O)OC3)CCC12O |
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| Storage condition | -20℃ |
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Synonyms
| Desoxostrophanthidin |
| Bio-0181 |
| Periplogenin |
