CAS 907577-50-8|m-PEG16-NH2

Introduction:Basic information about CAS 907577-50-8|m-PEG16-NH2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namem-PEG16-NH2
CAS Number907577-50-8Molecular Weight735.89800
Density/Boiling Point/
Molecular FormulaC33H69NO16Melting Point/
MSDS/Flash Point/

Names

NameMeO-16eg-NH2
SynonymMore Synonyms

m-PEG16-NH2 BiologicalActivity

Descriptionm-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Chemical & Physical Properties

Molecular FormulaC33H69NO16
Molecular Weight735.89800
Exact Mass735.46200
PSA173.70000
LogP0.54080

Synonyms

mPEG16-NH2
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