Introduction：Basic information about CAS 30315-93-6|L-Arg(Me, Me)-OH (asymmetrical), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | L-Arg(Me, Me)-OH (asymmetrical) |
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| CAS Number | 30315-93-6 | Molecular Weight | 202.25400 |
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| Density | 1.239g/cm3 | Boiling Point | 372.555°C at 760 mmHg |
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| Molecular Formula | C8H18N4O2 | Melting Point | / |
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| MSDS | / | Flash Point | 179.115°C |
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Names
| Name | Nω,Nω-dimethyl-L-arginine |
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| Synonym | More Synonyms |
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L-Arg(Me, Me)-OH (asymmetrical) BiologicalActivity
| Description | Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>NO SynthaseResearch Areas >>Cardiovascular DiseaseNatural Products >>Others |
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| Target | Human Endogenous Metabolite |
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| In Vitro | Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states. Asymmetric dimethylarginine (ADMA) is elevated in HIV-1 infection[1]. |
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| References | [1]. Hudson CL, et al. The cardiovascular risk marker asymmetric dimethylarginine is elevated in asymptomatic, untreated HIV-1 infection and correlates with markers of immune activation and disease progression. Ann Clin Biochem. 2014 Sep;51(Pt 5):568-75. |
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Chemical & Physical Properties
| Density | 1.239g/cm3 |
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| Boiling Point | 372.555°C at 760 mmHg |
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| Molecular Formula | C8H18N4O2 |
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| Molecular Weight | 202.25400 |
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| Flash Point | 179.115°C |
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| Exact Mass | 202.14300 |
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| PSA | 102.44000 |
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| LogP | 0.45540 |
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| InChIKey | YDGMGEXADBMOMJ-LURJTMIESA-N |
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| SMILES | CN(C)C(N)=NCCCC(N)C(=O)O |
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Safety Information
Customs
| HS Code | 2925290090 |
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| Summary | 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Synonyms
| N(omega),N(omega)-dimethyl-L-arginine |
| N,N-Dimethylarginine |
| 2-AMINO-5-(3,3-DIMETHYLGUANIDINO)PENTANOIC ACID |
| NG,NG-dimethyl-L-arginine |
| L-ORNITHINE,N5-[(DIMETHYLAMINO)IMINOMETHYL]- |
| asymmetric NG,NG-dimethyl-L-arginine |
| N-Hydroxyoxalyl-anthranilsaeure |
| NG,NG-dimethylarginine |
| L-Arg(Me, Me)-OH (asymmetrical) |
| (2S)-2-Amino-5-[(Amino-Dimethylaminomethylidene)Amino]Pentanoic Acid |
