Introduction：Basic information about CAS 26750-81-2|Alibendol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Alibendol |
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| CAS Number | 26750-81-2 | Molecular Weight | 251.278 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 402.4±45.0 °C at 760 mmHg |
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| Molecular Formula | C13H17NO4 | Melting Point | 98-101ºC |
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| MSDS | / | Flash Point | 197.2±28.7 °C |
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Names
| Name | 2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-prop-2-enylbenzamide |
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| Synonym | More Synonyms |
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Alibendol BiologicalActivity
| Description | Alibendol is an antispasmodic,choleretic, and cholekinetic. Target: Othersadministration of alibendol in beagle dogs, observed retention times were approximately 5.0 min for alibendol. The within-run precision showed RSD values between 5.83 and 16.96 %. The between-run RSD values varied from 6.73 to 17.99 % at the LLOQ [1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Endocrinology |
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| References | [1]. Sheng, L., H. Chen, and Y. Li, A HPLC method for determination of nicousamide in dog plasma and its application to pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci, 2007. 854(1-2): p. 99-103. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 402.4±45.0 °C at 760 mmHg |
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| Melting Point | 98-101ºC |
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| Molecular Formula | C13H17NO4 |
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| Molecular Weight | 251.278 |
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| Flash Point | 197.2±28.7 °C |
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| Exact Mass | 251.115753 |
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| PSA | 78.79000 |
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| LogP | 1.15 |
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| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
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| Index of Refraction | 1.564 |
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| InChIKey | UMJHTFHIQDEGKB-UHFFFAOYSA-N |
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| SMILES | C=CCc1cc(OC)c(O)c(C(=O)NCCO)c1 |
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| Storage condition | Refrigerator |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- CU8730000
- CHEMICAL NAME :
- Benzamide, 5-allyl-2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-
- CAS REGISTRY NUMBER :
- 26750-81-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C13-H17-N-O4
- MOLECULAR WEIGHT :
- 251.31
- WISWESSER LINE NOTATION :
- Q2MVR BQ CO1 E2U1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 5,188,1970
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Safety Information
Customs
| HS Code | 2924299090 |
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| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 2-Hydroxy-3-methoxy-5-allyl-N-(b-hydroxyethyl)benzamide |
| MFCD00865165 |
| EINECS 247-960-9 |
| Cebera |
| 2-Hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(2-propenyl)benzamide |
| 5-Allyl-2-hydroxy-N-(2-hydroxyethyl)-3-methoxybenzamide |
| 5-Allyl-2-hydroxy-N-(2-hydroxyethyl)-m-anisamide |
| FC 54 |
| Benzamide, 2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(2-propen-1-yl)- |
| 2-Hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(prop-2-en-1-yl)benzolcarboxamid |
| Alibendol |
