CAS 15664-29-6|Pheophorbide A
| Common Name | Pheophorbide A | ||
|---|---|---|---|
| CAS Number | 15664-29-6 | Molecular Weight | 592.68 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1019.0±65.0 °C at 760 mmHg |
| Molecular Formula | C35H36N4O5 | Melting Point | 191-195°C (lit.) |
| MSDS | ChineseUSA | Flash Point | 570.1±34.3 °C |
Names
| Name | pheophorbide a |
|---|---|
| Synonym | More Synonyms |
Pheophorbide A BiologicalActivity
| Description | Pheophorbide A is an intermediate product in the chlorophyll degradation pathway and can be used as a photosensitizer. Pheophorbide A acts as a lymphovascular activator with antitumor activity[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| References | [1]. Jihye Kim, et al. Pheophorbide a identified in an Eupatorium perfoliatum extract is a novel lymphatic vascular activator. Biomed Pharmacother. 2022 Mar;147:112664. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1019.0±65.0 °C at 760 mmHg |
| Melting Point | 191-195°C (lit.) |
| Molecular Formula | C35H36N4O5 |
| Molecular Weight | 592.68 |
| Flash Point | 570.1±34.3 °C |
| Exact Mass | 592.268555 |
| PSA | 136.97000 |
| LogP | 6.76 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.630 |
| InChIKey | RKEBXTALJSALNU-LDCXZXNSSA-N |
| SMILES | C=CC1=C(C)C2=NC1=CC1=NC(=CC3=C(C)C4=C(O)C(C(=O)OC)C(=C5NC(=C2)C(C)C5CCC(=O)O)C4=N3)C(CC)=C1C |
Safety Information
| Hazard Codes | Xn |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles9
More Articles| Antioxidant-photosensitizer dual-loaded polymeric micelles with controllable production of reactive oxygen species. Int. J. Pharm. 471(1-2) , 339-48, (2014) Poly(ethylene glycol)-b-poly(caprolactone) (PEG-b-PCL) micelles dually loaded with both pheophorbide a (PhA) as a photosensitizer and β-carotene (CAR) as a singlet oxygen ((1)O2) scavenger were design... | |
| In-vitro evidence of enhanced breast cancer resistance protein-mediated intestinal urate secretion by uremic toxins in Caco-2 cells. J. Pharm. Pharmacol. 67(2) , 170-7, (2015) It has been reported that intestinal urate excretion is increased at chronic kidney disease (CKD) state. In this report, whether uremic toxins are involved in the upregulation of intestinal breast can... | |
| ABCG2 transporter inhibitor restores the sensitivity of triple negative breast cancer cells to aminolevulinic acid-mediated photodynamic therapy. Sci. Rep. 5 , 13298, (2015) Photosensitizer protoporphyrin IX (PpIX) fluorescence, intracellular localization and cell response to photodynamic therapy (PDT) were analyzed in MCF10A normal breast epithelial cells and a panel of ... |
Synonyms
| Inchi=1/C35H36N4o5/C1-8-19-15(3)22-12-24-17(5)21(10-11-28(40)41)32(38-24)30-31(35(43)44-7)34(42)29-18(6)25(39-33(29)30)14-27-20(9-2)16(4)23(37-27)13-26(19)36-22/H8,12-14,17,21,31,36,39H,1,9-11H2,2-7H3,(H,40,41)/B22-12-,23-13-,24-12-,25-14-,26-13-,27-14 |
| 3-[(3S,4S,21R)-9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxophorbin-3-yl]propanoic acid |
| EINECS 239-738-5 |
| [3s-(3alpha,4beta,21beta)]-ramethyl-20-oxo |
| 3-phorbinepropanoicacid,9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tet |
| 13-Epi-phaeophorbide-a |
| Rel-3-[(3R,4R)-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbin-3-yl]propanoic acid |
| 3-[(3S,4S,21R)-14-Ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbin-3-yl]propanoic acid |
| 3-Phorbinepropanoic acid,9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-,(3S,4S) |
| [3S-(3alpha,4beta,21beta)]-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbine-3-propionic acid |
| (3S,4S)-9-Ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid |
| Pheophorbide A |
| (3S-(3a,4b,21b))-14-Ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbine-3-propionic Acid |
| 3-[(3S,4S,21R)-14-Ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinyl-3-phorbinyl]propanoic acid |
| 3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-, (3S,4S,21R)- |
| Demagnesia chloric acid -a |
