CAS 15529-90-5|CHLORO(TRIETHYLPHOSPHINE)GOLD(I)
Introduction：Basic information about CAS 15529-90-5|CHLORO(TRIETHYLPHOSPHINE)GOLD(I), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | CHLORO(TRIETHYLPHOSPHINE)GOLD(I) | ||
|---|---|---|---|
| CAS Number | 15529-90-5 | Molecular Weight | 350.57700 |
| Density | / | Boiling Point | 210ºC0.03 mm Hg(lit.) |
| Molecular Formula | C6H15AuClP | Melting Point | 84-86ºC(lit.) |
| MSDS | ChineseUSA | Flash Point | 27.2ºC |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | chloro(triethylphosphine)gold(i) |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Boiling Point | 210ºC0.03 mm Hg(lit.) |
|---|---|
| Melting Point | 84-86ºC(lit.) |
| Molecular Formula | C6H15AuClP |
| Molecular Weight | 350.57700 |
| Flash Point | 27.2ºC |
| Exact Mass | 350.02700 |
| PSA | 13.59000 |
| LogP | 3.21500 |
| Appearance of Characters | crystal | white to pink |
| InChIKey | SYBBXLKWGHAVHP-UHFFFAOYSA-N |
| SMILES | CC[PH+](CC)CC.Cl[Au] |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 79 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 68 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 92560 ug/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 46280 ug/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Cells - not otherwise specified
- DOSE/DURATION :
- 37500 nmol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 34,3243,1985
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Cells - not otherwise specified
- DOSE/DURATION :
- 37500 nmol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 34,3243,1985
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 + H311 + H331-H315-H319-H335 |
| Precautionary Statements | P261-P280-P301 + P310-P305 + P351 + P338-P311 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T: Toxic; |
| Risk Phrases | R23/24/25 |
| Safety Phrases | 26-28-36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | MD5431000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
Articles21
More Articles| Synthesis of thionato(triethylphosphine) gold(I) complexes:analogues of "auranofin," an antiarthritic drug. J. Inorg. Biochem. 38(2) , 95-100, (1990) New compounds having the formula [L-Au-PEt3]Cl (where L = imidazolidine-2-thione(Imt) and 1,3-Diazinane-2-thione(Diaz)) are synthesized. They are characterized by elemental analysis, infrared, 13C and... | |
| Inhibition of human phospholipase C by aurothiomalate and (triethylphosphine) gold complexes. Arzneimittelforschung 42(3) , 328-33, (1992) The effect of several gold complexes on the activity of phospholipase C from human blood platelets was studied in vitro. Aurothiomalate and auranofin--2 agents used for the chrysotherapy of rheumatoid... | |
| The structural flexibility of ferric cytochrome c: regulation of the spin-state equilibrium by an anti-arthritic gold(I) compound at neutral pH. FEBS Lett. 116(2) , 227-30, (1980) |
Synonyms
| Gold,chloro(triethylphosphine) |
| [Au(PEt3)Cl] |
| chloro(triethylphosphine)-gol |
| TRIETHYLPHOSPHINEGOLD I CHLORIDE |
| chloro(triethylphosphine)gold |
| [AuCl(PEt3)] |
| PEt3 gold(I) chloro complex |
| EINECS 239-572-3 |
| MFCD00013205 |
| Triethylphosphineaurous chloride |
| triethylphosphinegold |
