Introduction：Basic information about CAS 55028-72-3|Cloprostenol Sodium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cloprostenol Sodium |
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| CAS Number | 55028-72-3 | Molecular Weight | 446.897 |
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| Density | / | Boiling Point | 628ºC at 760 mmHg |
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| Molecular Formula | C22H28ClNaO6 | Melting Point | 68-70ºC |
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| MSDS | ChineseUSA | Flash Point | 333.6ºC |
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Names
| Name | (+/-)-Cloprostenol sodium salt hydrate |
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| Synonym | More Synonyms |
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Cloprostenol Sodium BiologicalActivity
| Description | Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a PGF2α receptor agonist[2] and is a luteolytic agent[1]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Prostaglandin Receptor |
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| In Vivo | Cloprostenol sodium salt (25 μg) decreases plasma progesterone in pregnant rats[1]. |
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| References | [1]. Salazar H, et al. Luteolytic effects of a prostaglandin analogue, cloprostenol (ICI 80,996), in rats: ultrastructural and biochemical observations. Biol Reprod. 1976 May;14(4):458-72. [2]. Pastel E, et al. Aldose reductases influence prostaglandin F2α levels and adipocyte differentiation in male mouse and human species. Endocrinology. 2015 May;156(5):1671-84. |
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Chemical & Physical Properties
| Boiling Point | 628ºC at 760 mmHg |
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| Melting Point | 68-70ºC |
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| Molecular Formula | C22H28ClNaO6 |
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| Molecular Weight | 446.897 |
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| Flash Point | 333.6ºC |
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| Exact Mass | 446.147217 |
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| PSA | 110.05000 |
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| LogP | 1.86030 |
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| InChIKey | IFEJLMHZNQJGQU-KCRDTMQASA-M |
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| SMILES | O=C([O-])CCCC=CCC1C(O)CC(O)C1C=CC(O)COc1cccc(Cl)c1.[Na+] |
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| Storage condition | −20°C |
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| Water Solubility | H2O: >10 mg/mL |
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Safety Information
| Hazard Codes | T:Toxic; |
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| Risk Phrases | R60;R22;R36/37/38 |
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| Safety Phrases | S53-S26-S36/37/39-S45 |
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| WGK Germany | 3 |
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Synonyms
| 5-Heptenoic acid, 7-((1R,2R,3R,5S)-2-((1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl)-3,5-dihydroxycyclopentyl)-, monosodium salt, (5Z)-rel- |
| EINECS 259-439-3 |
| Sodium (5Z)-7-{(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoate |
| (±)-Sodium (Z)-7-((1R*,2R*,3R*,5S*)-2-((E)-(3R*)-4-(m-Chlorophenoxy)-3-hydroxy-1-butenyl)-3,5-dihydroxycyclopentyl)-5-heptenoate |
| MFCD00132875 |
| Cloprostenol Sodium |
| Sodium (5Z)-7-{(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl}-5-heptenoate |
| 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, sodium salt, (5Z)- (1:1) |
| UNII:886SAV9675 |
| (5Z)-rel-7-((1R,2R,3R,5S)-2-((1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl)-3,5-dihydroxycyclopentyl)-5-heptenoic Acid Monosodium Salt |
| (±)-Cloprostenol sodium |
