Introduction：Basic information about CAS 129-18-0|phenylbutazone sodium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | phenylbutazone sodium |
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| CAS Number | 129-18-0 | Molecular Weight | 330.356 |
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| Density | 1.063 g/mL at 25 °C(lit.) | Boiling Point | 113 °C27 mm Hg(lit.) |
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| Molecular Formula | C19H19N2NaO2 | Melting Point | / |
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| MSDS | / | Flash Point | 95 °C |
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Names
| Name | Sodium butazolidine |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.063 g/mL at 25 °C(lit.) |
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| Boiling Point | 113 °C27 mm Hg(lit.) |
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| Molecular Formula | C19H19N2NaO2 |
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| Molecular Weight | 330.356 |
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| Flash Point | 95 °C |
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| Exact Mass | 330.134430 |
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| PSA | 49.99000 |
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| LogP | 4.11460 |
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| Index of Refraction | n20/D 1.516(lit.) |
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| InChIKey | VYOUHDLOIRJOSW-UHFFFAOYSA-N |
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| SMILES | CCCC[c-]1c(=O)n(-c2ccccc2)n(-c2ccccc2)c1=O.[Na+] |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UQ8300000
- CHEMICAL NAME :
- 3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-, monosodium salt
- CAS REGISTRY NUMBER :
- 129-18-0
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C19-H20-N2-O2.Na
- MOLECULAR WEIGHT :
- 331.40
- WISWESSER LINE NOTATION :
- T5VNNV EHJ BR& CR& E4 &-NA-
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 16 mg/kg/D
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Blood - agranulocytosis Skin and Appendages - dermatitis, other (after systemic exposure)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 855 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 310 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 113 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 476 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 169 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 257 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 94 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 146 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 2160 umol/L
- REFERENCE :
- HUMAA7 Humangenetik. (Heidelberg, Fed. Rep. Ger.) V.1-30, 1964-75. For publisher information, see HUGEDQ. Volume(issue)/page/year: 12,330,1971
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Safety Information
| Hazard Codes | C |
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| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
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| Safety Phrases | S26-S36 |
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| HS Code | 2934100090 |
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Customs
| HS Code | 2934100090 |
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| Summary | 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
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Synonyms
| PHENYLBUTAZONE SODIUM |
| 3,5-dioxo-1,2-diphenyl-4-n-butylpyrazolidinsodium |
| 4-BUTYL-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE SODIUM |
| Einecs 204-935-7 |
| diphenyldioxobutylpyrazolidine-butazolidine-sodium |
| Phenylbutazone sodium salt |
| PHENYL BUTAZONE SODIUM SALT |
| sodiumphenylbutazone |
| MFCD01749404 |
| Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide |
| UNII:189M850I32 |
| butazolidinesodium |
