CAS 110590-64-2|H-Tyr-Ile-Gly-Ser-Arg-OH trifluoroacetate salt
| Common Name | H-Tyr-Ile-Gly-Ser-Arg-OH trifluoroacetate salt | ||
|---|---|---|---|
| CAS Number | 110590-64-2 | Molecular Weight | 594.66000 |
| Density | 1.44 g/cm3 | Boiling Point | / |
| Molecular Formula | C26H42N8O8 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | tyr-ile-gly-ser-arg |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | YIGSR is a peptide that can inhibit the tumour growth and metastasis of leukaemic cells[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| References | [1]. N Yoshida, et al. The laminin-derived peptide YIGSR (Tyr–Ile–Gly–Ser–Arg) inhibits human pre-B leukaemic cell growth and dissemination to organs in SCID mice. Br J Cancer. 1999 Aug; 80(12): 1898–1904. |
Chemical & Physical Properties
| Density | 1.44 g/cm3 |
|---|---|
| Molecular Formula | C26H42N8O8 |
| Molecular Weight | 594.66000 |
| Exact Mass | 594.31300 |
| PSA | 282.08000 |
| LogP | 0.67370 |
| Index of Refraction | 1.633 |
| InChIKey | MWOGMBZGFFZBMK-LJZWMIMPSA-N |
| SMILES | CCC(C)C(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCN=C(N)N)C(=O)O |
| Storage condition | -20℃ |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles29
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| Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor. FASEB J. 20(7) , 906-15, (2006) It has been reported that extracellular matrix (ECM) molecules regulate monocyte activation by binding with a 67 kDa nonintegrin laminin receptor (LR). As microgliosis is a pivotal factor in propellin... | |
| Malignancy-related 67kDa laminin receptor in adenoid cystic carcinoma. Effect on migration and beta-catenin expression. Oral Oncol. 43(10) , 987-98, (2007) Adenoid cystic carcinoma is a malignant salivary gland neoplasm with recurrence and metastasis. We studied the expression of a malignancy-related non-integrin laminin receptor, the 67LR, in this neopl... |
Synonyms
| tyrosyl-isoleucyl-glycyl-seryl-arginine |
| Laminin Fragment 929-933 |
| LAMININ FRAGMENT 929-933 |
| LAMININ B1 CHAIN PENTAPEPTIDE FRAGMENT |
| Laminin (929-933) |
| LAMININ FRAGMENT |
| LAMININ PENTAPEPTIDE |
| YIGSR |
| Tyrosinyl-isoleucinyl-glycinyl-serinyl-arginine |
