Introduction：Basic information about CAS 352431-50-6|17β-Estradiol sulfate-d4 sodium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 17β-Estradiol sulfate-d4 sodium |
|---|
| CAS Number | 352431-50-6 | Molecular Weight | 378.45 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C18H19D4NaO5S | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | sodium 17beta-estradiol-2,4,16,16-d4 3-sulfate |
|---|
| Synonym | More Synonyms |
|---|
17β-Estradiol sulfate-d4 sodium BiologicalActivity
| Description | 17β-Estradiol sulfate-d4 (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid[1][2]. |
|---|
| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorSignaling Pathways >>Neuronal Signaling >>GABA Receptor |
|---|
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
|---|
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Li W, et al. Neuroactive steroids and human recombinant rho1 GABAC receptors. J Pharmacol Exp Ther. 2007;323(1):236-247. [3]. Schneider C, et al. A novel enzyme-linked immunosorbent assay for ethynylestradiol using a long-chain biotinylated EE2 derivative. Steroids. 2004;69(4):245-253. |
|---|
Chemical & Physical Properties
| Molecular Formula | C18H19D4NaO5S |
|---|
| Molecular Weight | 378.45 |
|---|
| Exact Mass | 378.141510 |
|---|
| PSA | 95.04000 |
|---|
| LogP | 3.82340 |
|---|
| InChIKey | LMJQCTISQYSLPF-LDBFCMRTSA-M |
|---|
| SMILES | CC12CCC3c4ccc(OS(=O)(=O)[O-])cc4CCC3C1CCC2O.[Na+] |
|---|
Synonyms
| Estra-1,3,5(10)-triene-2,4,16,16-d-3,17-diol, 3-(hydrogen sulfate), sodium salt, (17β)- (1:1) |
| Sodium (17β)-17-hydroxy(2,4,16,16-H)estra-1,3,5(10)-trien-3-yl sulfate |
