Introduction：Basic information about CAS 260367-12-2|Fmoc-NH-PEG1-CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fmoc-NH-PEG1-CH2COOH |
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| CAS Number | 260367-12-2 | Molecular Weight | 341.358 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 563.8±50.0 °C at 760 mmHg |
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| Molecular Formula | C19H19NO5 | Melting Point | / |
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| MSDS | / | Flash Point | 294.8±30.1 °C |
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Names
| Name | 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]acetic acid |
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| Synonym | More Synonyms |
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Fmoc-NH-PEG1-CH2COOH BiologicalActivity
| Description | Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Lorenzo Benatuil, et al. Anti-cd98 antibodies and antibody drug conjugates. WO2017214456A. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 563.8±50.0 °C at 760 mmHg |
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| Molecular Formula | C19H19NO5 |
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| Molecular Weight | 341.358 |
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| Flash Point | 294.8±30.1 °C |
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| Exact Mass | 341.126312 |
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| PSA | 84.86000 |
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| LogP | 3.18 |
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| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
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| Index of Refraction | 1.630 |
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| InChIKey | LBVXPUINIMIGAU-UHFFFAOYSA-N |
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| SMILES | O=C(O)COCCNC(=O)OCC1c2ccccc2-c2ccccc21 |
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Safety Information
Customs
| HS Code | 2924299090 |
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| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Acetic acid, 2-[2-[9H-fluoren-9-yl(methoxycarbonyl)amino]ethoxy]- |
| Acetic acid, 2-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethoxy]- |
| Fmoc-O1Pen-OH |
| (2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)acetic acid |
| {2-[9H-Fluoren-9-yl(methoxycarbonyl)amino]ethoxy}acetic acid |
| 2-(2-(((9H-fluoren-9-yl)methoxy)carbonylamino)ethoxy)acetic acid |
