CAS 127770-45-0|5-(and-6)-carboxy-2`,7`-dichlorofluorescein diacetate
| Common Name | 5-(and-6)-carboxy-2`,7`-dichlorofluorescein diacetate | ||
|---|---|---|---|
| CAS Number | 127770-45-0 | Molecular Weight | 529.279 |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 743.3±60.0 °C at 760 mmHg |
| Molecular Formula | C25H14Cl2O9 | Melting Point | 210ºC (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 403.3±32.9 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 5(6)-carboxy-2',7'-dichlorofluorescein diacetate |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is a cell permeant fluorescent indicator. 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate can be used to assess ROS generation within human neuronal-glial (HNG) cells in primary co-culture[1] |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Pogue AI, et al. Metal-sulfate induced generation of ROS in human brain cells: detection using an isomeric mixture of 5- and 6-carboxy-2',7'-dichlorofluorescein diacetate (carboxy-DCFDA) as a cell permeant tracer. Int J Mol Sci. 2012;13(8):9615-26. |
Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 743.3±60.0 °C at 760 mmHg |
| Melting Point | 210ºC (dec.)(lit.) |
| Molecular Formula | C25H14Cl2O9 |
| Molecular Weight | 529.279 |
| Flash Point | 403.3±32.9 °C |
| Exact Mass | 528.001465 |
| PSA | 125.43000 |
| LogP | 3.66 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.712 |
| Storage condition | -20°C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
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Synonyms
| 5-(6)-CDCFDA [5(6)-Carboxy-2',7'-dichlorofluorescein Diacetate] |
| Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 3',6'-bis(acetyloxy)-2',7'-dichloro-3-oxo- |
| 3',6'-Diacetoxy-2',7'-dichloro-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid |
