CAS 4376-18-5|Monomethyl phthalate

Introduction:Basic information about CAS 4376-18-5|Monomethyl phthalate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMonomethyl phthalate
CAS Number4376-18-5Molecular Weight180.157
Density1.3±0.1 g/cm3Boiling Point328.9±25.0 °C at 760 mmHg
Molecular FormulaC9H8O4Melting Point82-84 °C(lit.)
MSDSChineseUSAFlash Point134.7±16.7 °C
Symbol
GHS07
Signal WordWarning

Names

Namemethyl hydrogen phthalate
SynonymMore Synonyms

Monomethyl phthalate BiologicalActivity

DescriptionMonomethyl phthalate is a phthalate metabolite. Monomethyl phthalate acts as a urinary biomarker of phthalates exposure and can be used as a standard for the determination of thyroid cancer and benign nodule[1].
Related CatalogResearch Areas >>Cancer
References

[1]. Chong Liu, et al. Urinary biomarkers of phthalates exposure and risks of thyroid cancer and benign nodule. J Hazard Mater. 2020 Feb 5;383:121189.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point328.9±25.0 °C at 760 mmHg
Melting Point82-84 °C(lit.)
Molecular FormulaC9H8O4
Molecular Weight180.157
Flash Point134.7±16.7 °C
Exact Mass180.042252
PSA63.60000
LogP1.13
Vapour Pressure0.0±0.8 mmHg at 25°C
Index of Refraction1.556
Storage conditionRefrigerator

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
RIDADRNONH for all modes of transport
WGK Germany3

Articles6

More Articles
Feasibility of ultra-high performance liquid and gas chromatography coupled to mass spectrometry for accurate determination of primary and secondary phthalate metabolites in urine samples.

Anal. Chim. Acta 853 , 625-36, (2014)

Phthalates (PAEs) are ubiquitous toxic chemical compounds. During the last few years, some phthalate metabolites (MPAEs) have been proposed as appropriate biomarkers in human urine samples to determin...

Monitoring of PAEMs and beta-agonists in urine for a small group of experimental subjects and PAEs and beta-agonists in drinking water consumed by the same subjects.

J. Hazard. Mater. 277 , 169-79, (2014)

This 5-month study contains two parts: (1) to monitor the concentrations of 11 phthalate esters metabolites (PAEMs) and two beta-agonists in human urine samples collected from a small group of consent...

Phthalate Metabolites in Urine Samples from School Children in Taipei, Taiwan.

Arch. Environ. Contam. Toxicol. 69 , 202-7, (2015)

In 2011, Taiwan authorities reported that two phthalates, including di-(2-ethylhexyl) phthalate and di-iso-nonyl phthalate, were intentionally introduced into a variety of foods and beverages during t...

Synonyms

1,2-Benzenedicarboxylic acid, monomethyl ester
Phthalic acid methyl ester
2-methoxycarbonylbenzoic acid
2-(Methoxycarbonyl)benzoic acid
Monomethyl phthalate
METHYL HYDROGEN PHTHALATE
phthalic acid, mono-methyl ester
MFCD00002466
1,2-Benzenedicarboxylic acid monomethyl ester
EINECS 224-476-6
Phthalic acid monomethyl ester
mono-Methyl phthalate
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