Introduction:Basic information about CAS 85679-70-5|Osteocalcin (45-49) (human), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Osteocalcin (45-49) (human) |
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| CAS Number | 85679-70-5 | Molecular Weight | 581.66000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C30H39N5O7 | Melting Point | / |
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| MSDS | USA | Flash Point | / |
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Names
| Name | 2-[[1-[2-[[2-[(2-amino-3-phenylpropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoic acid |
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| Synonym | More Synonyms |
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Osteocalcin (45-49) (human) BiologicalActivity
| Description | Bone Gla Protein (45-49) is the 45-49 fragment of gamma-carboxyglutamic acid (GLA)-containing protein from bone (BGP, osteocalcin), which has chemotactic activity in vitro for a number of cells which are found adjacent to endosteal bone surfaces in vivo[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| In Vitro | Bovine bone Gla protein (BGP) (1 nM-10 μM) exerts chemotactic activity of (0.1 and 1 μM) cultured human breast cancer cells (MDA-MB-231 cells), (1 nM-1 μM) human peripheral blood monocytes, and (1-10 μM) rat osteosarcoma cells with osteoblast-like characteristics[1]. |
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| References | [1]. Mundy GR, et al. Chemotactic activity of the gamma-carboxyglutamic acid containing protein in bone. Calcif Tissue Int. 1983;35(2):164-8. |
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Chemical & Physical Properties
| Molecular Formula | C30H39N5O7 |
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| Molecular Weight | 581.66000 |
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| Exact Mass | 581.28500 |
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| PSA | 191.16000 |
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| LogP | 2.13300 |
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| InChIKey | MJAFJCRCGVXXTP-IGRGDXOOSA-N |
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| SMILES | CC(C)C(NC(=O)C1CCCN1C(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)Cc1ccccc1)C(=O)O |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| OSTEOCALCIN,Fragment 45-49 |
| Phe-Tyr-Gly-Pro-Val |
| Osteocalcin Fragment 45-49 human |
| FYGPV |