CAS 122-18-9|Cetalkonium chloride
| Common Name | Cetalkonium chloride | ||
|---|---|---|---|
| CAS Number | 122-18-9 | Molecular Weight | 396.092 |
| Density | / | Boiling Point | / |
| Molecular Formula | C25H46ClN | Melting Point | 55-65 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS05, GHS07, GHS09 | Signal Word | Danger |
Names
| Name | Benzyldimethylhexadecylammonium chloride |
|---|---|
| Synonym | More Synonyms |
Cetalkonium chloride BiologicalActivity
| Description | Cetalkonium chloride is an ammonium antiseptic agent used in many topical drugs for infections of mouth, throat and eye. Cetalkonium chloride acts as anti-inflammatory amphiphilic agent[1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Cesar Torres-Luna, et al. Formation of Drug-Participating Catanionic Aggregates for Extended Delivery of Non-Steroidal Anti-Inflammatory Drugs from Contact Lenses. Biomolecules. 2019 Oct 10;9(10):593. |
Chemical & Physical Properties
| Melting Point | 55-65 °C(lit.) |
|---|---|
| Molecular Formula | C25H46ClN |
| Molecular Weight | 396.092 |
| Exact Mass | 395.331879 |
| LogP | 4.74830 |
| InChIKey | SXPWTBGAZSPLHA-UHFFFAOYSA-M |
| SMILES | CCCCCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1.[Cl-] |
| Water Solubility | MODERATELY SOLUBLE |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,349,1959
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,349,1959 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,39,1953 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9945 No. of Facilities: 386 (estimated) No. of Industries: 9 No. of Occupations: 10 No. of Employees: 5332 (estimated) No. of Female Employees: 389 (estimated)
Safety Information
| Symbol | GHS05, GHS07, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302 + H312-H314-H400 |
| Precautionary Statements | P273-P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | C:Corrosive;N:Dangerousfortheenvironment; |
| Risk Phrases | R21/22;R34;R50 |
| Safety Phrases | S61-S45-S36/37/39-S26 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | BO6822450 |
| Hazard Class | 9.0 |
| HS Code | 2923900090 |
Customs
| HS Code | 2923900090 |
|---|---|
| Summary | 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
Articles33
More Articles| Effect of the cationic surfactant moiety on the structure of water entrapped in two catanionic reverse micelles created from ionic liquid-like surfactants. ChemPhysChem 15(14) , 3097-109, (2014) The behavior of water entrapped in reverse micelles (RMs) formed by two catanionic ionic liquid-like surfactants, benzyl-n-hexadecyldimethylammonium 1,4-bis-2-ethylhexylsulfosuccinate (AOT-BHD) and ce... | |
| Characterization of antibiotic and disinfectant susceptibility profiles among Pseudomonas aeruginosa veterinary isolates recovered during 1994-2003. J. Appl. Microbiol. 118(2) , 326-42, (2015) To evaluate susceptibility of Pseudomonas aeruginosa veterinary isolates to antibiotics and disinfectants.Pseudomonas aeruginosa isolates collected from dogs (n = 155) and other animals (n = 20) from ... | |
| Determination of quaternary ammonium compounds in oranges and cucumbers using QuEChERS extraction and ultra-performance liquid chromatography/tandem mass spectrometry. J. AOAC Int. 97(4) , 1021-6, (2014) A simple and fast method has been developed for determining relevant quaternary ammonium compounds in cucumber and orange samples. The target compounds were benzoalkonium chloride (BAC-10, BAC-12, BAC... |
Synonyms
| N-hexadecyl-N,N-dimethyl-N-benzylammonium chloride |
| dimethylbenzylhexadecylammonium chloride |
| Cetyldimethylbenzylammonium |
| hexadecyldimethylbenzylammonium chloride |
| EINECS 204-526-3 |
| Acquat CDAC |
| acinol |
| Cetol |
| Cetylbenzyldimethylammonium chloride |
| benzyl-dimethyl-cetylammonium chloride |
| MFCD00011625 |
| benzyl-dimethyl-hexadecyl-ammonium chloride |
| dmcbac |
| CKC |
| benzyl-n-hexadecyldimethyl ammonium chloride |
| Cetalkonium chloride |
| N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride |
| 16-BAC,Benzylhexadecyldimet |
| cdbac |
| Cetyldimethylbenzylammonium chloride |
| Ammonyx T |
| banicol |
| Benzylhexadecyldimethylammonium Chloride Hydrate |
| Benzylcetyldimethylammonium Chloride Hydrate |
| N-Benzyl-N,N-dimethyl-1-hexadecanaminium chloride |
| win357 |
| Acetoquat CDAC |
| spilan |
| Benzyldimethyl-n-hexadecylammonium chloride |
| benzylhexadecyldimethylammonium chloride |
| Benzenemethanaminium, N-hexadecyl-N,N-dimethyl-, chloride (1:1) |
| Zettyn |
| cetylon |
| bonjela |
| Ammonyx G |
| HDBAC |
| Benzyldimethylhexadecylammonium Chloride Hydrate |
