CAS 301-02-0|Oleamide

Introduction：Basic information about CAS 301-02-0|Oleamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Oleamide BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Articles45
7. Synonyms

Common Name	Oleamide
CAS Number	301-02-0	Molecular Weight	281.477
Density	0.9±0.1 g/cm3	Boiling Point	433.3±24.0 °C at 760 mmHg
Molecular Formula	C₁₈H₃₅NO	Melting Point	70°C
MSDS	ChineseUSA	Flash Point	215.9±22.9 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	oleamide
Synonym	More Synonyms

Oleamide BiologicalActivity

Description	Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma.
Related Catalog	Natural Products >>OthersResearch Areas >>Others
Target	Human Endogenous Metabolite
In Vitro	Oleamide accumulates in the cerebrospinal fluid (CSF) of rats after six hours of sleep deprivation and induces sleep in naive rats and mice. Inhibition of the primary catabolic enzyme of oleamide (fatty acid amide hydrolase) by trifluoromethyl-octadecenone reduces sleep latency and increases total sleep time when given centrally to rats and peripherally to mice[1]
References	[1]. Mendelson WB, et al. The hypnotic actions of the fatty acid amide, oleamide. Neuropsychopharmacology. 2001 Nov;25(5 Suppl):S36-9.

Chemical & Physical Properties

Density	0.9±0.1 g/cm3
Boiling Point	433.3±24.0 °C at 760 mmHg
Melting Point	70°C
Molecular Formula	C₁₈H₃₅NO
Molecular Weight	281.477
Flash Point	215.9±22.9 °C
Exact Mass	281.271851
PSA	43.09000
LogP	6.75
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.469
InChIKey	FATBGEAMYMYZAF-KTKRTIGZSA-N
SMILES	CCCCCCCCC=CCCCCCCCC(N)=O
Storage condition	−20°C

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H317-H319-H335
Precautionary Statements	P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	1
HS Code	2924199090

Customs

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles45

Prymnesium parvum revisited: relationship between allelopathy, ichthyotoxicity, and chemical profiles in 5 strains.

Aquat. Toxicol. 157 , 159-66, (2014)

Bioassay-guided discovery of ichthyotoxic algal compounds using in vivo fish assays is labor intensive, costly, and highly regulated. Since the mode of action of most known algal-mediated fish-killing...

Preventive effects of a fermented dairy product against Alzheimer's disease and identification of a novel oleamide with enhanced microglial phagocytosis and anti-inflammatory activity.

PLoS ONE 10(3) , e0118512, (2015)

Despite the ever-increasing number of patients with dementia worldwide, fundamental therapeutic approaches to this condition have not been established. Epidemiological studies suggest that intake of f...

Connexin 43 expressed in endothelial cells modulates monocyte‑endothelial adhesion by regulating cell adhesion proteins.

Mol. Med. Report. 12 , 7146-52, (2015)

Adhesion between circulating monocytes and vascular endothelial cells is a key initiator of atherosclerosis. In our previous studies, it was demonstrated that the expression of connexin (Cx)43 in mono...

Synonyms

(9Z)-9-Octadecenamide

oleicacidamide-heptaglycolether

9-Octadecenamide, (9Z)-

9-Octadecenimidic acid, (9Z)-

Oleic acid amide

9-Octadecenoic acid, amide (cis)

Adogen 73

EINECS 206-103-9

9-Octadecenamide, (Z)- (9CI)

Amide O

OLEAMID

Armid O

MFCD00053638

Slip-eze

(9Z)-9-Octadecenimidic acid

AMD-O

(Z)-9-Octadecenamide

9-Octadecenamide, (Z)-

cis-9,10-Octadecenoamide cis-9-Octadecenamide Oleic acid amide

cis-9,10-Octadecenoamide

cis-9-octadecenamide

Oleamide

9-cis-Oleamide

(9Z)-Octadec-9-enamide

Plastic additive 20

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