Introduction：Basic information about CAS 30924-93-7|Boc-L-glutamic acid 1-benzyl ester, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Boc-L-glutamic acid 1-benzyl ester |
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| CAS Number | 30924-93-7 | Molecular Weight | 337.368 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 522.6±50.0 °C at 760 mmHg |
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| Molecular Formula | C17H23NO6 | Melting Point | 97 °C |
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| MSDS | ChineseUSA | Flash Point | 269.9±30.1 °C |
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Names
| Name | (4S)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxo-5-phenylmethoxypentanoic acid |
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| Synonym | More Synonyms |
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Boc-L-glutamic acid 1-benzyl ester BiologicalActivity
| Description | Boc-Glu-OBzl is a glutamic acid derivative[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| In Vitro | Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1]. |
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| References | [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 522.6±50.0 °C at 760 mmHg |
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| Melting Point | 97 °C |
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| Molecular Formula | C17H23NO6 |
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| Molecular Weight | 337.368 |
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| Flash Point | 269.9±30.1 °C |
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| Exact Mass | 337.152527 |
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| PSA | 101.93000 |
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| LogP | 3.34 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.524 |
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| InChIKey | CVZUKWBYQQYBTF-ZDUSSCGKSA-N |
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| SMILES | CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)OCc1ccccc1 |
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| Storage condition | −20°C |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
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| Safety Phrases | 22-24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2924299090 |
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Customs
| HS Code | 2924299090 |
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| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Articles4
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| Stability and in vitro metabolism of dipeptide model prodrugs with affinity for the oligopeptide transporter. Eur. J. Pharm. Sci. 11 , 43-50, (2000) One approach to increase drug stability and to facilitate oral absorption of low bioavailability drugs may be to design oligopeptide ester prodrugs which are stable in the gastrointestinal tract, are ... | |
| Side reactions in solid-phase peptide synthesis and their applications. Int. J. Pept. Protein Res. 48 , 292-298, (1996) Side reactions in peptide synthesis indicate steps needing improvement as well as opportunities for structural diversification in combinatorial design. Among the side reactions observed in this study,... | |
| Modification of the vitamin K-dependent carboxylase assay. J. Biochem. Biophys. Methods 11 , 59, (1985) Methods are presented that describe alternative protocols for the isolation of rat liver microsomes containing the vitamin K-dependent carboxylase and the procedure in which the solubilized enzyme is ... | |
Synonyms
| N-α-tert-BOC-L-glutamic-γ-benzyl ester |
| Boc-L-glutamic acid 1-benzyl ester |
| (2S)-5-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-5-oxopentanoic acid (non-preferred name) |
| Boc-Glu-OBzl |
| 5-Benzyl N-(tert-Butoxycarbonyl)-L-glutamate |
| L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 5-(phenylmethyl) ester |
| Boc-L-glutamic acid 5-benzyl ester |
| 5-Benzyl N-Boc-L-glutamate |
| MFCD00065568 |
| N-t-butoxycarbonyl-L-glutamic acid benzyl ester |
| B-Glu-BE |
| Boc-(S)-glutamic acid benzyl ester |
| (2S)-5-(Benzyloxy)-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid |
| (4S)-5-(Benzyloxy)-4-[(tert-butoxycarbonyl)amino]-5-oxopentanoic acid (non-preferred name) |
| (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxo-5-phenylmethoxypentanoic acid |
| Boc-L-Glutamicacid1-benzylester |
| Boc-Glu(Obzl)-OH |
| N-Boc-L-glutamic Acid 5-Benzyl Ester |
| (4S)-5-(Benzyloxy)-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-oxopentanoic acid |
| N-(tert-Butoxycarbonyl)-L-glutamic Acid 1-Benzyl Ester |
| N-(tert-Butoxycarbonyl)-L-glutamic acid 5-benzyl ester |
| Boc-L-Glutamic acid 5-benzylester |
| Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(phenylmethyl) ester |
| N-Boc-L-glutamic Acid 1-Benzyl Ester |
| 1-Benzyl N-(tert-Butoxycarbonyl)-L-glutamate |
| 1-Benzyl N-Boc-L-glutamate |
| Boc-L-glutamic acid α-benzylester |
