CAS 673-06-3|D-phenylalanine

Introduction：Basic information about CAS 673-06-3|D-phenylalanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. D-phenylalanine BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles19
8. Synonyms

Common Name	D-phenylalanine
CAS Number	673-06-3	Molecular Weight	165.189
Density	1.2±0.1 g/cm3	Boiling Point	307.5±30.0 °C at 760 mmHg
Molecular Formula	C₉H₁₁NO₂	Melting Point	273-276 °C(lit.)
MSDS	USA	Flash Point	139.8±24.6 °C

Names

Name	D-phenylalanine
Synonym	More Synonyms

D-phenylalanine BiologicalActivity

Description	D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Li E, et al. D-Phenylalanine inhibits biofilm development of a marine microbe, Pseudoalteromonas sp. SC2014. FEMS Microbiol Lett. 2016 Sep;363(18).

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	307.5±30.0 °C at 760 mmHg
Melting Point	273-276 °C(lit.)
Molecular Formula	C₉H₁₁NO₂
Molecular Weight	165.189
Flash Point	139.8±24.6 °C
Exact Mass	165.078979
PSA	63.32000
LogP	1.11
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.576
InChIKey	COLNVLDHVKWLRT-MRVPVSSYSA-N
SMILES	NC(Cc1ccccc1)C(=O)O
Water Solubility	27 g/L (20 ºC)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY7533000

CHEMICAL NAME :: Alanine, phenyl-, D-

CAS REGISTRY NUMBER :: 673-06-3

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H11-N-O2

MOLECULAR WEIGHT :: 165.21

WISWESSER LINE NOTATION :: QVYZ1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 500 mg/kg/5W-I

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 1(3),124,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5452 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 64,319,1956 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5535 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 307 (estimated) No. of Female Employees: 251 (estimated)

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R34
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	AY7533000
HS Code	29224995

Customs

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles19

Improved gate effect enantioselectivity of phenylalanine-imprinted polymers in water by blending crosslinkers.

Anal. Chim. Acta 862 , 77-85, (2015)

In this work, the anodic current at an electrode grafted with a molecularly imprinted polymer (MIP) crosslinked via a combination of hydrophobic ethyleneglycol dimethacrylate (EDMA) and hydrophilic me...

Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease.

Eur. J. Med. Chem. 44 , 3922-9, (2009)

Colon-specific mutual azo prodrugs of 5-aminosalicylic acid with essential amino acids were synthesized for the management of inflammatory bowel disease. The structures were confirmed by elemental and...

Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.

Bioorg. Med. Chem. 16 , 3530-6, (2008)

The first activation study of the human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms associated to tumors, hCA IX and XII, with a small library of natural and non-natural amino acids as well as aroma...

Synonyms

(S)-phenylalanine

L-Phenylalanine

H-D-Phe-OH

(2S)-2-amino-3-phenylpropanoic acid

L-PHENYLALININE

α-Amino-β-phenylpropionic acid, L-

H-Phe-OH

Alanine, 3-phenyl-

L-phenylalanine zwitterion

S-phenylalanine

D-b-Phenylalanine

D-β-Phenylalanine

(S)-(-)-Phenylalanine

(R)-Phenylalanine

(S)-a-Amino-b-phenylpropionic Acid

Alanine, phenyl-, L-

L-2-Amino-3-phenylpropionic acid

(S)-2-Amino-3-phenylpropionic acid

(S)-2-Amino-3-phenylpropanoic acid

D-a-Amino-b-phenylpropionic Acid

C6H5CH2CH(NH2)COOH

(S)-a-Aminohydrocinnamic Acid

D-α-Amino-β-phenylpropionic acid

Phenylalanine

α-Aminohydrocinnamic acid, L-

(L)-Phenylalanine

Phenylalanine (VAN)

Phenylalanine, L-

phenylalanine D-form

Benzenepropanoic acid, α-amino-, (S)-

l-Phe

EINECS 211-603-5

PhE

D-phenylalanine zwitterion

β-phenyl-L-alanine

d-Phe

(-)-Phenylalanine

(S)-α-Aminobenzenepropanoic acid

MFCD00004270

(R)-(+)-Phenylalanine

α-Amino-β-phenylpropionic acid

(2R)-2-amino-3-phenylpropanoic acid

(S)-A-Aminobenzenepropanoic Acid

D-Phenylalanine

D-alpha-Amino-beta-phenylpropionic acid

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