CAS 120143-22-8|1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose

Introduction：Basic information about CAS 120143-22-8|1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose
CAS Number	120143-22-8	Molecular Weight	377.35
Density	/	Boiling Point	/
Molecular Formula	C₁₇H₁₉N₃O₇	Melting Point	/
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS07	Signal Word	Warning

Names

Name	1,2-di-o-acetyl-3-azido-3-deoxy-5-o-toluoyl-d-ribofuranose
Synonym	More Synonyms

BiologicalActivity

Description	1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

Molecular Formula	C₁₇H₁₉N₃O₇
Molecular Weight	377.35
Exact Mass	377.12200
PSA	137.88000
LogP	1.50316
InChIKey	WLSQDUZXMHIZCA-BOEXNKMNSA-N
SMILES	CC(=O)OC1OC(COC(=O)c2ccccc2C)C(N=[N+]=[N-])C1OC(C)=O

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312
Precautionary Statements	P280
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
RIDADR	NONH for all modes of transport

Synonyms

3-azido-1,2-bis-O-acetyl-5-O-toluoyl-3-deoxy-D-ribofuranose

3-Azido-1H-[1,2,4]triazol

1H-1,2,4-Triazole,3-azido

3-Azido-1,2,4-triazol

3-azido-1H-[1,2,4]triazole

3-Azido-1,2,4-triazole

3-azido-1,2-di-O-acetyl-5-O-(p-toluoyl)-3-deoxy-D-ribofuranose

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