Introduction：Basic information about CAS 1927-31-7|2'-Deoxyadenosine-5'-triphosphate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Deoxyadenosine-5'-triphosphate |
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| CAS Number | 1927-31-7 | Molecular Weight | 535.145 |
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| Density | 2.5±0.1 g/cm3 | Boiling Point | 913.3±75.0 °C at 760 mmHg |
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| Molecular Formula | C10H14N5Na2O12P3 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 506.1±37.1 °C |
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Names
| Name | dATP |
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| Synonym | More Synonyms |
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2'-Deoxyadenosine-5'-triphosphate BiologicalActivity
| Description | 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase[1]. |
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| Related Catalog | Research Areas >>Others |
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| References | [1]. P J Romaniuk, A study of the mechanism of T4 DNA polymerase with diastereomeric phosphorothioate analogues of deoxyadenosine triphosphate. J Biol Chem. 1982 Jul 10;257(13):7684-8. |
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Chemical & Physical Properties
| Density | 2.5±0.1 g/cm3 |
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| Boiling Point | 913.3±75.0 °C at 760 mmHg |
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| Molecular Formula | C10H14N5Na2O12P3 |
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| Molecular Weight | 535.145 |
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| Flash Point | 506.1±37.1 °C |
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| Exact Mass | 534.964722 |
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| PSA | 321.68000 |
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| LogP | -4.93 |
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| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
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| Index of Refraction | 1.874 |
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| InChIKey | SUYVUBYJARFZHO-RRKCRQDMSA-N |
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| SMILES | Nc1ncnc2c1ncn2C1CC(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1 |
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| Storage condition | −20°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AU7358800
- CHEMICAL NAME :
- Adenosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate)
- CAS REGISTRY NUMBER :
- 1927-31-7
- BEILSTEIN REFERENCE NO. :
- 0071964
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C10-H16-N5-O12-P3
- MOLECULAR WEIGHT :
- 491.22
- WISWESSER LINE NOTATION :
- T56 BN DN FN HNT&J IZ D- ET5OTJ B1OPQO&OPQO&OPQQO CQ
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 33600 nmol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,2092,1982
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | AU7358800 |
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| Packaging Group | III |
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Articles32
More Articles
| Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states. Biochim. Biophys. Acta 1824(4) , 679-91, (2012) The ribosome inactivating proteins (RIPs) of type 1 are plant toxins that eliminate adenine base selectively from the single stranded loop of rRNA. We report six crystal structures, type 1 RIP from Mo... | |
| Mechanism and fidelity of HIV reverse transcriptase. J. Biol. Chem. 267 , 25988-25997, (1992) We have examined the RNA-dependent and DNA-dependent polymerase and ribonuclease H catalytic activities of human immunodeficiency virus reverse transcriptase using rapid transient kinetic methods with... | |
| Human immunodeficiency virus reverse transcriptase: steady-state and pre-steady-state kinetics of nucleotide incorporation. Biochemistry 31 , 4473-4479, (1992) Steady-state and pre-steady-state kinetic constants were determined for reverse transcriptase catalyzed incorporation of nucleotides and nucleotide analogues into defined-sequence DNA primed-RNA templ... | |
Synonyms
| 5'-DATP |
| DATP,LI |
| Disodium 2'-deoxy-5'-O-({[(phosphonooxy)phosphinato]oxy}phosphinato)adenosine |
| 2'-Deoxy-ATP |
| deoxyribose adenosine triphosphate |
| Deoxyadenosine triphosphate |
| Adenosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate) |
| EINECS 217-662-3 |
| 2'-Deoxyadenosine-5'-triphosphate disodium salt |
| 2'-Datp |
| 2'-DEOXYADENOSINE-5'-TRIPHOSHATE |
| DATP LI-SALT |
| 2'-Deoxyadenosine 5'-(tetrahydrogen triphosphate) |
| deoxyadenosinetriphosphate |
| deoxy-atp |
| [32P]-2'-Deoxyadenosine triphosphate |
| dATP |
| Adenosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate), sodium salt (1:2) |
| 2'-Deoxyadenosine-5'-triphosphate |
| deoxyadenosine-triphosphate |
| 2'-Deoxyadenosine 5'-triphosphate |
| MFCD00672265 |
