CAS 149838-22-2|FM1-43

Introduction:Basic information about CAS 149838-22-2|FM1-43, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameFM1-43
CAS Number149838-22-2Molecular Weight611.53800
Density/Boiling Point/
Molecular FormulaC30H49Br2N3Melting Point/
MSDSUSAFlash Point/

Names

NameFM 1-43 dye
SynonymMore Synonyms

FM1-43 BiologicalActivity

DescriptionFM1-43, a styryl dye used to study endocytosis and exocytosis, behaves as a permeant blocker of the hair-cell mechanotransducer channel. FM1-43 also reduces the ototoxic effects of the aminoglycoside antibiotic neomycin sulfate[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References

[1]. J E Gale, et al. FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel. J Neurosci. 2001 Sep 15;21(18):7013-25.

Chemical & Physical Properties

Molecular FormulaC30H49Br2N3
Molecular Weight611.53800
Exact Mass609.22900
PSA7.12000
LogP0.82570
InChIKeyVZUVCAGXYLMFEC-UHFFFAOYSA-L
SMILESCCCCN(CCCC)c1ccc(C=Cc2cc[n+](CCC[N+](CC)(CC)CC)cc2)cc1.[Br-].[Br-]

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport

Articles90

More Articles
Regulation of density of functional presynaptic terminals by local energy supply.

Mol. Brain 8 , 42, (2015)

The density of functional synapses is an important parameter in determining the efficacy of synaptic transmission. However, how functional presynaptic terminal density is regulated under natural physi...

A genomic region encompassing a newly identified exon provides enhancing activity sufficient for normal myo7aa expression in zebrafish sensory hair cells.

Dev. Neurobiol. 75 , 961-83, (2015)

MYO7A is an unconventional myosin involved in the structural organization of hair bundles at the apex of sensory hair cells (SHCs) where it serves mechanotransduction in the process of hearing and bal...

A newly designed molecule J2326 for Alzheimer's disease disaggregates amyloid fibrils and induces neurite outgrowth.

Neuropharmacology 92 , 146-57, (2015)

Alzheimer's disease is a neurodegenerative disorder characterized by deposition of β-amyloid (Aβ) fibrils accompanied with progressive neurite loss. None of the clinically approved anti-Alzheimer's ag...

Synonyms

Neurodye GH1-43
3-[4-[(E)-2-[4-(dibutylamino)phenyl]ethenyl]pyridin-1-ium-1-yl]propyl-triethylazanium,dibromide
SynaptoGreen™ C4
N-(3-Triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide
N-(3-TRIETHYLAMMONIUMPROPYL)-4-(4-(DIBUTYLAMINO)STYRYL)PYRIDINIUM DIBROMIDE
CAS 36536-22-8|DiIC1(5)
CAS 87687-03-4|Resorufin pentyl ether
Recommended......
TOP