CAS 80529-93-7|GADOPENTETIC ACID

Introduction：Basic information about CAS 80529-93-7|GADOPENTETIC ACID, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. GADOPENTETIC ACID BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	GADOPENTETIC ACID
CAS Number	80529-93-7	Molecular Weight	547.57300
Density	/	Boiling Point	721.1ºC at 760 mmHg
Molecular Formula	C₁₄H₂₀GdN₃O₁₀	Melting Point	129ºC (dec.)(lit.)
MSDS	/	Flash Point	389.9ºC

Names

Name	gadopentetic acid
Synonym	More Synonyms

GADOPENTETIC ACID BiologicalActivity

Description	Gadopentetic acid (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies. The initial concentration of Gadopentetic acid (Gd-DTPA) in the plasma ([Gd-DTPA0]) is an important parameter for DCE-MRI. [Gd-DTPA0] is related to the administered bolus dose and varies with subjects. A bolus of 0.025 mmol/kg Gd-DTPA offers shorter acquisition time and less exposure of subjects, with a half-life of 37.3 mins, a mean residence time of 53.8 mins, and an AUC of 3.37 ± 0.47 mmol/min/L[1].
Related Catalog	Research Areas >>Others
References	[1]. Wan C, et al. Gd-DTPA-induced dynamic metabonomic changes in rat biofluids. Magn Reson Imaging. 2017 Dec;44:15-25. [2]. Taheri S, et al. Analysis of pharmacokinetics of Gd-DTPA for dynamic contrast-enhanced magnetic resonance imaging. Magn Reson Imaging. 2016 Sep;34(7):1034-40.

Description

Gadopentetic acid (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies. The initial concentration of Gadopentetic acid (Gd-DTPA) in the plasma ([Gd-DTPA0]) is an important parameter for DCE-MRI. [Gd-DTPA0] is related to the administered bolus dose and varies with subjects. A bolus of 0.025 mmol/kg Gd-DTPA offers shorter acquisition time and less exposure of subjects, with a half-life of 37.3 mins, a mean residence time of 53.8 mins, and an AUC of 3.37 ± 0.47 mmol/min/L[1].

Related Catalog

Research Areas >>Others

References

[1]. Wan C, et al. Gd-DTPA-induced dynamic metabonomic changes in rat biofluids. Magn Reson Imaging. 2017 Dec;44:15-25.

[2]. Taheri S, et al. Analysis of pharmacokinetics of Gd-DTPA for dynamic contrast-enhanced magnetic resonance imaging. Magn Reson Imaging. 2016 Sep;34(7):1034-40.

Chemical & Physical Properties

Boiling Point	721.1ºC at 760 mmHg
Melting Point	129ºC (dec.)(lit.)
Molecular Formula	C₁₄H₂₀GdN₃O₁₀
Molecular Weight	547.57300
Flash Point	389.9ºC
Exact Mass	548.03900
PSA	204.71000
InChIKey	IZOOGPBRAOKZFK-UHFFFAOYSA-K
SMILES	O=C([O-])CN(CCN(CC(=O)[O-])CC(=O)[O-])CCN(CC(=O)[O-])CC(=O)[O-].[Gd+3].[H+].[H+]

Safety Information

Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26-37/39
WGK Germany	3

Synonyms

gadolinium diethylenetriaminepentaacetic acid

Acido gadopentetico

GADOPENTETATE

Gd acid spray

Acide gadopentetique

Acidum gadopenteticum

Gd(diethylenetriaminepentaacetic acid(-3H))

gadolinium 1,1,4,7,7-diethylenetriaminepentaacetate

gadoliniumdtpa

Gd-DTPA

Gadopentetic

Recommended......