CAS 117467-28-4|Cefditoren pivoxil

Introduction：Basic information about CAS 117467-28-4|Cefditoren pivoxil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Cefditoren pivoxil BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Cefditoren pivoxil
CAS Number	117467-28-4	Molecular Weight	620.721
Density	1.6±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₂₅H₂₈N₆O₇S₃	Melting Point	207-209ºC
MSDS	/	Flash Point	/

Names

Name	cefditoren pivoxil
Synonym	More Synonyms

Cefditoren pivoxil BiologicalActivity

Description	Cefditoren pivoxil is a new-third generation cephalosporin antibiotic that has a broad spectrum of activity against Gram-positive and Gram-negative bacteria, including common respiratory and skin pathogens.Target: AntibacterialCefditoren pivoxil, a new-third generation cephalosporin antibiotic that has recently been granted approval in Spain, shows important activity over a large part of the pathogens causing skin, soft tissue and respiratory tract infections, including Gram-negative and Gram-positive bacteria. Cefditoren is also marketed under the name Meiact. Cefditoren has a broad spectrum of activity and has been used to treat bacterial infections of the skin and respiratory tract including bronchitis, pneumonia, and tonsillitis. The following represents MIC susceptibility data for a few medically significant microorganisms.Cefditoren has shown excellent in vitro activity against the Gram-positive pathogens penicillin-susceptible and -intermediate Streptococcus pneumoniae, S. pyogenes and methicillin-susceptible Staphylococcus aureus. Cefditoren was inactive against methicillin-resistant S. aureus. Of the important Gram-negative pathogens, cefditoren had potent antibacterial effects against beta-lactamase-positive and -negative Haemophilus influenzae, H. parainfluenzae and beta-lactamase-positive and -negative Moraxella catarrhalis.
Related Catalog	Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection
References	[1]. Hernández-Martin J, et al. Cefditoren pivoxil: A new oral cephalosporin for skin, soft tissue and respiratory tract infections. Rev Esp Quimioter. 2006 Sep;19(3):231-46. [2]. Darkes MJ, et al. Cefditoren pivoxil. Drugs. 2002;62(2):319-36; discussion 337-8.

Description

Cefditoren pivoxil is a new-third generation cephalosporin antibiotic that has a broad spectrum of activity against Gram-positive and Gram-negative bacteria, including common respiratory and skin pathogens.Target: AntibacterialCefditoren pivoxil, a new-third generation cephalosporin antibiotic that has recently been granted approval in Spain, shows important activity over a large part of the pathogens causing skin, soft tissue and respiratory tract infections, including Gram-negative and Gram-positive bacteria. Cefditoren is also marketed under the name Meiact. Cefditoren has a broad spectrum of activity and has been used to treat bacterial infections of the skin and respiratory tract including bronchitis, pneumonia, and tonsillitis. The following represents MIC susceptibility data for a few medically significant microorganisms.Cefditoren has shown excellent in vitro activity against the Gram-positive pathogens penicillin-susceptible and -intermediate Streptococcus pneumoniae, S. pyogenes and methicillin-susceptible Staphylococcus aureus. Cefditoren was inactive against methicillin-resistant S. aureus. Of the important Gram-negative pathogens, cefditoren had potent antibacterial effects against beta-lactamase-positive and -negative Haemophilus influenzae, H. parainfluenzae and beta-lactamase-positive and -negative Moraxella catarrhalis.

Related Catalog

Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection

References

[1]. Hernández-Martin J, et al. Cefditoren pivoxil: A new oral cephalosporin for skin, soft tissue and respiratory tract infections. Rev Esp Quimioter. 2006 Sep;19(3):231-46.

[2]. Darkes MJ, et al. Cefditoren pivoxil. Drugs. 2002;62(2):319-36; discussion 337-8.

Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Melting Point	207-209ºC
Molecular Formula	C₂₅H₂₈N₆O₇S₃
Molecular Weight	620.721
Exact Mass	620.118164
PSA	257.18000
LogP	2.74
Index of Refraction	1.710
InChIKey	AFZFFLVORLEPPO-SJESJDBISA-N
SMILES	CON=C(C(=O)NC1C(=O)N2C(C(=O)OCOC(=O)C(C)(C)C)=C(C=Cc3scnc3C)CSC12)c1csc(N)n1
Storage condition	-20?C Freezer

Safety Information

Hazard Codes	Xi
RIDADR	NONH for all modes of transport
HS Code	2941905990

Customs

HS Code	2941905990

Synonyms

Meiact

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-3-[(Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-

Spectracef

Cefditoren pivoxil

Cefditoren pivoxyl

[(2,2-Dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(Z)-2-(4-methyl-1,3-thiazol-5-yl)vinyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

[(2,2-dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

MFCD00933166

Cefditoren Pivaloyloxymethyl Ester

Cefditoren (Pivoxil)

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