CAS 125678-68-4|Myristoyl-Lys-Arg-Thr-Leu-Arg-OH

Introduction：Basic information about CAS 125678-68-4|Myristoyl-Lys-Arg-Thr-Leu-Arg-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMyristoyl-Lys-Arg-Thr-Leu-Arg-OH
CAS Number125678-68-4Molecular Weight883.17600
Density1.26g/cm3Boiling Point/
Molecular FormulaC42H82N12O8Melting Point/
MSDS/Flash Point/

Names

Name(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-6-amino-2-(tetradecanoylamino)hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
SynonymMore Synonyms

Myristoyl-Lys-Arg-Thr-Leu-Arg-OH BiologicalActivity

DescriptionN-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat[1].
Related CatalogSignaling Pathways >>Epigenetics >>PKCResearch Areas >>Inflammation/ImmunologySignaling Pathways >>TGF-beta/Smad >>PKC
In VitroN-Myristoyl-Lys-Arg-Thr-Leu-Arg (0-50 μM) inhibits the production and release of IL-2 from cultured Jurkat cells stimulated with TPA plus either PHA or OKT3 mAb[1].

Chemical & Physical Properties

Density1.26g/cm3
Molecular FormulaC42H82N12O8
Molecular Weight883.17600
Exact Mass882.63800
PSA352.85000
LogP6.31520
Index of Refraction1.582
InChIKeyUCADRBIEWWELGN-PGMVXXSLSA-N
SMILESCCCCCCCCCCCCCC(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)O)C(C)O

Synonyms

N-Myristoyl-lysyl-arginyl-threonyl-leucyl-arginine
MYRISTOYL-KRTLR-OH
Mlatla
MYRISTOYL-KRTLR-OH INHIBITOR OF PKC
N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH
N-Myristyl-lys-arg-thr-leu-arg
N2-(N-(N-(N2-(N2-(1-Oxotetradecyl)-L-lysyl)-L-arginyl)-L-threonyl)-L-leucyl)-L-arginine
CAS 54364-02-2|8-PCPT-CGMP, TEA
CAS 135304-08-4|ac-cys(farnesyl)-ome
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