CAS 145229-76-1|TRAP-7 trifluoroacetate salt

Introduction:Basic information about CAS 145229-76-1|TRAP-7 trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTRAP-7 trifluoroacetate salt
CAS Number145229-76-1Molecular Weight845.98500
Density1.41 g/cm3Boiling Point/
Molecular FormulaC39H63N11O10Melting Point/
MSDS/Flash Point/

Names

Nameh-ser-phe-leu-leu-arg-asn-pro-oh
SynonymMore Synonyms

TRAP-7 trifluoroacetate salt BiologicalActivity

DescriptionTRAP-7 is a thrombin receptor (PAR) activating peptide. TRAP-7 stimulates total inositol phosphate (IP) accumulation and phosphorylation of a specific endogenous substrate for activated PKC. TRAP-7 can be used in cardiovascular disease research[1].
Related CatalogResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>Protease-Activated Receptor (PAR)
References

[1]. Webb ML, et al. Effects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of smooth muscle cell thrombin receptors. Biochem Pharmacol. 1993 Apr 22;45(8):1577-82.  

Chemical & Physical Properties

Density1.41 g/cm3
Molecular FormulaC39H63N11O10
Molecular Weight845.98500
Exact Mass845.47600
PSA354.35000
LogP1.76310
Index of Refraction1.64
InChIKeyFHZSIZRTNHGLSX-FLMSMKGQSA-N
SMILESCC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)C(N)CO)C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC(N)=O)C(=O)N1CCCC1C(=O)O

Synonyms

thrombinreceptorpeptidesfllrnp
SER-PHE-LEU-LEU-ARG-ASN-PRO
SFLLRNP
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