Introduction:Basic information about CAS 26929-65-7|2'-Azido-2'-deoxyuridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Azido-2'-deoxyuridine |
|---|
| CAS Number | 26929-65-7 | Molecular Weight | 269.214 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C9H11N5O5 | Melting Point | 149-153ºC |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | 2′-Azido-2′-deoxyuridine |
|---|
| Synonym | More Synonyms |
|---|
2'-Azido-2'-deoxyuridine BiologicalActivity
| Description | 2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA Synthesis |
|---|
| In Vitro | 2'-Azido-2'-deoxyuridine (N3dUrd) has IC50s of >350 μM for ribonucleotide reductase activity in chinese hamster ovary (CHO) and 3T6 cell[1]. |
|---|
| References | [1]. Kang SH, et al. Biological activity and phosphorylation of 2'-azido-2'-deoxyuridine and 2'-azido-2'-deoxycytidine. Nucleosides Nucleotides. 1998 Jun;17(6):1077-88. |
|---|
Chemical & Physical Properties
| Melting Point | 149-153ºC |
|---|
| Molecular Formula | C9H11N5O5 |
|---|
| Molecular Weight | 269.214 |
|---|
| Exact Mass | 269.076019 |
|---|
| PSA | 154.30000 |
|---|
| LogP | -1.10 |
|---|
| InChIKey | MRUKYOQQKHNMFI-UHFFFAOYSA-N |
|---|
| SMILES | [N-]=[N+]=NC1C(O)C(CO)OC1n1ccc(=O)[nH]c1=O |
|---|
| Storage condition | 2-8°C |
|---|
Safety Information
| Hazard Codes | Xi: Irritant; |
|---|
| Risk Phrases | R36/37/38 |
|---|
| Safety Phrases | S22-S24/25 |
|---|
| WGK Germany | 3 |
|---|
| HS Code | 2934999090 |
|---|
Customs
| HS Code | 2934999090 |
|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Synonyms
| Uridine, 2'-azido-2'-deoxy- |
| 2'-Azido-2'-deoxyuridine |