Introduction：Basic information about CAS 15958-92-6|(Des-Arg9)-Bradykinin acetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (Des-Arg9)-Bradykinin acetate salt |
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| CAS Number | 15958-92-6 | Molecular Weight | 904.023 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C44H61N11O10 | Melting Point | / |
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| MSDS | USA | Flash Point | / |
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Names
| Name | [Des-Arg9]-Bradykinin |
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| Synonym | More Synonyms |
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(Des-Arg9)-Bradykinin acetate salt BiologicalActivity
| Description | [Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Bradykinin ReceptorResearch Areas >>Inflammation/ImmunologyPeptides |
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| Target | Bradykinin (B1) receptor[1] |
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| In Vitro | The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1]. |
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| References | [1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Molecular Formula | C44H61N11O10 |
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| Molecular Weight | 904.023 |
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| Exact Mass | 903.460266 |
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| PSA | 322.78000 |
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| LogP | 0.64 |
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| Index of Refraction | 1.687 |
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| InChIKey | VCEHWDBVPZFHAG-POFDKVPJSA-N |
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| SMILES | NC(N)=NCCCC(N)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)O |
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| Storage condition | -20°C |
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Synonyms
| L-phenylalanine, N-[[(2S)-1-[(2S)-2-[[(1Z,2S)-2-[[(1E)-2-[[(1Z)-[(2S)-1-[[(2S)-1-[(2S)-2-amino-5-[(aminoiminomethyl)amino]-1-oxopentyl]-2-pyrrolidinyl]carbonyl]-2-pyrrolidinyl]hydroxymethylene]amino]-1-hydroxyethylidene]amino]-1-hydroxy-3-phenylpropylidene]amino]-3-hydroxy-1-oxopropyl]-2-pyrrolidinyl]hydroxymethylene]-, (Z)- |
| 1-8-Bradykinin |
| des-arginine9-bradykinin |
| bradykinin fragment 1-8 |
| 9-Des-Arg-bk |
| [des-Arg(9)]-bradykinin |
| 9-De-Arg-bradykinin |
| L-Phenylalanine, N-(diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl- |
| des-Arg9-bradykinin |
| RPPGFSPF |
| DABK |
| N-(Diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine |
| des-Arg9-BK |
| Bradykinin[Des-Arg9] |
