Introduction：Basic information about CAS 154-08-5|DL-5-Fluorotryptophan, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | DL-5-Fluorotryptophan |
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| CAS Number | 154-08-5 | Molecular Weight | 222.216 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 450.7±45.0 °C at 760 mmHg |
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| Molecular Formula | C11H11FN2O2 | Melting Point | 265 °C (dec.)(lit.) |
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| MSDS | ChineseUSA | Flash Point | 226.4±28.7 °C |
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Names
| Name | 5-fluorotryptophan |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 450.7±45.0 °C at 760 mmHg |
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| Melting Point | 265 °C (dec.)(lit.) |
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| Molecular Formula | C11H11FN2O2 |
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| Molecular Weight | 222.216 |
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| Flash Point | 226.4±28.7 °C |
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| Exact Mass | 222.080460 |
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| PSA | 79.11000 |
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| LogP | 1.17 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.673 |
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| InChIKey | INPQIVHQSQUEAJ-UHFFFAOYSA-N |
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| SMILES | NC(Cc1c[nH]c2ccc(F)cc12)C(=O)O |
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| Storage condition | 2-8°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- YN6825000
- CHEMICAL NAME :
- Tryptophan, 5-fluoro-, DL-
- CAS REGISTRY NUMBER :
- 154-08-5
- BEILSTEIN REFERENCE NO. :
- 0022753
- LAST UPDATED :
- 199803
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C11-H11-F-N2-O2
- MOLECULAR WEIGHT :
- 222.24
- WISWESSER LINE NOTATION :
- T56 BMJ D1YZVQ GF
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 776 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 15,2134,1966
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36/38 |
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| Safety Phrases | S22-S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | YN6825000 |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles28
More Articles
| Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin. J. Med. Chem. 49(15) , 4616-22, (2006) Tryptophans at positions 4 and 7 of compstatin, a peptide complement inhibitor, are crucial for its interaction with C3. However, the nature of their involvement has not been studied to date. Here we ... | |
| Ionization potentials of fluoroindoles and the origin of nonexponential tryptophan fluorescence decay in proteins. J. Am. Chem. Soc. 127(11) , 4104-13, (2005) This work reports an explanation for the unusual monoexponential fluorescence decay of 5-fluorotryptophan (5FTrp) in single-Trp mutant proteins [Broos, J.; Maddalena, F.; Hesp, B. H. J. Am. Chem. Soc.... | |
| In vivo synthesized proteins with monoexponential fluorescence decay kinetics. J. Am. Chem. Soc. 126(1) , 22-3, (2004) Tryptophan, when in a protein, typically shows multiexponential fluorescence decay kinetics. Complex kinetics prevents a straightforward interpretation of time-resolved fluorescence protein data, part... | |
Synonyms
| 2-amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid |
| 5-Fluoro-DL-tryptophan |
| H-5-FLUORO-DL-TRP-OH |
| 5-Fluoro D,L-tryptophan |
| 5-fluoro-DL-Trp |
| 5-Fluoro-D,L-tryptophan |
| DL-5-FLUOROTRYPTOPHAN |
| MFCD00005649 |
| EINECS 205-822-5 |
| 5-Fluorotryptophan |
| 5-Fluoro-DL-tryptophane |
| Tryptophan, 5-fluoro- |
